Dwiyana, Reiva Farah
BENEFICIAL EFFECT OF 20% SUNFLOWER SEED OIL CREAM O N MILD ATOPIC DERMATITIS IN CHILDREN - Vol.11(2) - M P Innovare Academic Sciences Pvt Ltd 2019 - 100-103p.
Objective:
The objective
of this study was t
o evaluate the beneficial effect of topical applications of 20% sunflower seed oil (
SSO
) in decreasing the
transepidermal water loss (
TEWL
) and
scoring
of
atopic dermatitis (SCORAD
) index value in mild atopic dermatitis
(AD)
pediatric patients in
Bandung, Indonesia.
Method
s:
This was
a randomized
study in
volving
20 children with mild AD (SCORAD
<25) in Bandung, Indonesia.
They were divided into 2 group
s:
the experimental group treated with 20% SSO cream
and the control group treated with a
common moisturizing
cream for four weeks.
The TEWL
score including SCORAD index
was
evaluated at baseline, week 1, week 2, and week 4.
Result
s:
A total of 20 participants completed the study. In the first week, the
control group had TEWL score
decrement
by
36.62%
while
the
experimental group
by
28.89%
(
p
=0.88). In the fourth week,
the
TEWL decrement
s of
the
experimental
and
control group were
by
56.94% and
52.50%, respectively (
p
=0.20),
and this was followed by an
improvement of SCORAD index in both treatment groups.
Conclusio
n:
The
20%
SSO
cream has a
beneficial effect in decreasing the TEWL score and improving SCORAD
ind
ices
. Therefore, it can be
considered as an alternative treatment for
mild AD among children
.
PHARMACEUTICS
BENEFICIAL EFFECT OF 20% SUNFLOWER SEED OIL CREAM O N MILD ATOPIC DERMATITIS IN CHILDREN - Vol.11(2) - M P Innovare Academic Sciences Pvt Ltd 2019 - 100-103p.
Objective:
The objective
of this study was t
o evaluate the beneficial effect of topical applications of 20% sunflower seed oil (
SSO
) in decreasing the
transepidermal water loss (
TEWL
) and
scoring
of
atopic dermatitis (SCORAD
) index value in mild atopic dermatitis
(AD)
pediatric patients in
Bandung, Indonesia.
Method
s:
This was
a randomized
study in
volving
20 children with mild AD (SCORAD
<25) in Bandung, Indonesia.
They were divided into 2 group
s:
the experimental group treated with 20% SSO cream
and the control group treated with a
common moisturizing
cream for four weeks.
The TEWL
score including SCORAD index
was
evaluated at baseline, week 1, week 2, and week 4.
Result
s:
A total of 20 participants completed the study. In the first week, the
control group had TEWL score
decrement
by
36.62%
while
the
experimental group
by
28.89%
(
p
=0.88). In the fourth week,
the
TEWL decrement
s of
the
experimental
and
control group were
by
56.94% and
52.50%, respectively (
p
=0.20),
and this was followed by an
improvement of SCORAD index in both treatment groups.
Conclusio
n:
The
20%
SSO
cream has a
beneficial effect in decreasing the TEWL score and improving SCORAD
ind
ices
. Therefore, it can be
considered as an alternative treatment for
mild AD among children
.
PHARMACEUTICS