Anusha, D.
Convenient synthesis and biological activities of N-(pyridin-3-ylmethylene) benzohydrazides by the condensation of nicotinaldehydes with benzohydrazides - Vol.60B(1), Jan. - New Delhi CSIR 2021 - 117-126p.
Series of N'-(pyridine-3-ylmethylene)benzohydrazides 3a-y have been prepared by the condensation of nicotinaldehydes 1a-e with benzohydrazides 2a-e in the presence of glacial AcOH in ethanol at room temperature. Total twenty five compounds have been prepared and confirmed based on spectral data. The compounds have been evaluated for anti-microbial, free radical scavenging (DPPH, ABTS.+) and α-glucosidase inhibitory activities. Compound 3h has shown potent anti-fungal activity. Compounds 3f-g and 3j have shown potent ABTS.+ free radical scavenging activity. Compound 3d has shown potent anti-hyperglycemic activity.
GENERAL CHEMISTRY
Convenient synthesis and biological activities of N-(pyridin-3-ylmethylene) benzohydrazides by the condensation of nicotinaldehydes with benzohydrazides - Vol.60B(1), Jan. - New Delhi CSIR 2021 - 117-126p.
Series of N'-(pyridine-3-ylmethylene)benzohydrazides 3a-y have been prepared by the condensation of nicotinaldehydes 1a-e with benzohydrazides 2a-e in the presence of glacial AcOH in ethanol at room temperature. Total twenty five compounds have been prepared and confirmed based on spectral data. The compounds have been evaluated for anti-microbial, free radical scavenging (DPPH, ABTS.+) and α-glucosidase inhibitory activities. Compound 3h has shown potent anti-fungal activity. Compounds 3f-g and 3j have shown potent ABTS.+ free radical scavenging activity. Compound 3d has shown potent anti-hyperglycemic activity.
GENERAL CHEMISTRY