Guglani, Anchala

Nutritional profile, phytochemical investigation and in vitro antioxidant activity of leaves extract of pyracantha crenulata collected from middle hill climatic conditions of western himalayas - Vol.84(1), Jan-Feb - Mumbai Indian Journal of Pharmaceutical Science 2022 - 182-188p.

Pyracantha crenulata (Deoxynivalenol) M. Roemis an evergreen shrub of family Rosaceae extensively
reported for antihypertensive, antispasmodic, diuretic, sedative and vasodilatation properties. Despite its
clinical uses, analysis of its nutritional profile and elemental composition, as well as the phytochemical
investigations revealed the other probable applications of the plant. Quantitative biochemical analysis
showed the presence of substantial quantities of carbohydrates, protein, crude, fibre and ascorbic acid
along with the physicochemical characteristic of the plant. The elemental composition analysis revealed
the presence of several macro elements and microelements, such as sodium, potassium, calcium, lithium,
zinc, copper, manganese, iron and cobalt. The phytochemical investigations confirm the presence of
medicinally active components such as alkaloids, saponins, glycosides, tannins and phenols. The in vitro
antioxidant activity assessed using 1,1-diphenyl-2-picrylhydrazyl, 2,2-azinobis(3-ethylbenzothiazoline-6-
sulfonic acid), scavenging assay and quantitative phytochemical analysis showed that the leaves extract
having IC50 value 10.61 μg/ml and 12.73 μg/ml, by 2,2-azinobis(3-ethylbenzothiazoline-6-sulfonic acid) and
1,1-diphenyl-2-picrylhydrazyl assay, and the phytochemical, such as total phenolic (128.78 mg/g), tannin
(385.15 mg/g) and flavonoid contents (22.81 mg/g) respectively. In essence, the lyophilized leaves extract
exhibits higher total phenolic, tannin and flavonoid contents and antioxidant activity. In summary, these
results provide insightful information that the leaves of the plant endowed with several active principles,
elemental composition and other biochemical characteristics that can be useful in the therapeutic activities
as well as for the nutritional applications.


PHARMACEUTICS
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