Shukla, A.
Comparative study of in vitro antioxidant potential, potoprotective screening of ehretia acuminata R.BR. leaves - Vol.56(9), Sep - Mumbai Indian Drug Manufacture's Association - IDMA 2019 - 30-36p.
To evaluate the comparability of some of the most common radical scavenging assays using 2,2′-azinobis-3-ethylbenzthiazoline-6-sulphonic acid (ABTS), 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical, Ferric reducing power assay (FRAP) & nitric oxide. leaves of traditionally important medicinal plant Ehretia acuminata, used in Chinese herbal medicine were identified & analyzed for their antioxidant capacity, total phenolic and flavonoid content & sun protective factor (SPF). In this study different organic solvents, petroleum ether 40-600 C (PE), chloroform (CH), ethyl acetate (EA), ethanol 99.9% (EOL) & water (AQ) were used for soxhlet exraction of E. acuminata leaves. Among them, ethyl acetate extract exhibited strongest antioxidant activity with IC50 between 99 to 250 μg/ml. Ascorbic acid (AA) used as a standard antioxidant exhibited IC50 25µg/ml. Petroleum ether showed weak free radical scavenging activity with IC50 value between 500 to 770 µg/ml. The ability of protection against UV-B region followed the trend EOL> EA> PE> AQ> CH extract. The result reveals that these natural antioxidant potential of E. acuminata represents a side effect-free alternative to synthetic antioxidants in the food processing industry, in sunscreen formulations and for use in preventive synthetic drugs
PHARMACEUTICS
Comparative study of in vitro antioxidant potential, potoprotective screening of ehretia acuminata R.BR. leaves - Vol.56(9), Sep - Mumbai Indian Drug Manufacture's Association - IDMA 2019 - 30-36p.
To evaluate the comparability of some of the most common radical scavenging assays using 2,2′-azinobis-3-ethylbenzthiazoline-6-sulphonic acid (ABTS), 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical, Ferric reducing power assay (FRAP) & nitric oxide. leaves of traditionally important medicinal plant Ehretia acuminata, used in Chinese herbal medicine were identified & analyzed for their antioxidant capacity, total phenolic and flavonoid content & sun protective factor (SPF). In this study different organic solvents, petroleum ether 40-600 C (PE), chloroform (CH), ethyl acetate (EA), ethanol 99.9% (EOL) & water (AQ) were used for soxhlet exraction of E. acuminata leaves. Among them, ethyl acetate extract exhibited strongest antioxidant activity with IC50 between 99 to 250 μg/ml. Ascorbic acid (AA) used as a standard antioxidant exhibited IC50 25µg/ml. Petroleum ether showed weak free radical scavenging activity with IC50 value between 500 to 770 µg/ml. The ability of protection against UV-B region followed the trend EOL> EA> PE> AQ> CH extract. The result reveals that these natural antioxidant potential of E. acuminata represents a side effect-free alternative to synthetic antioxidants in the food processing industry, in sunscreen formulations and for use in preventive synthetic drugs
PHARMACEUTICS