| 000 -LEADER |
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a |
| 003 - CONTROL NUMBER IDENTIFIER |
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| control field |
OSt |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
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| control field |
20191203104916.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
191202b xxu||||| |||| 00| 0 eng d |
| 040 ## - CATALOGING SOURCE |
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| Transcribing agency |
AIKTC-KRRC |
| Modifying agency |
AIKTC-KRRC |
| Original cataloging agency |
AIKTC-KRRC |
| 041 ## - LANGUAGE CODE |
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| Language code of text/sound track or separate title |
ENG |
| 082 ## - DEWEY DECIMAL CLASSIFICATION NUMBER |
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| Edition number |
DDC23 |
| 100 ## - MAIN ENTRY--PERSONAL NAME |
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| 9 (RLIN) |
10905 |
| Author |
Prasad, R. |
| 245 ## - TITLE STATEMENT |
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| Title |
Rutin-mediated Apoptosis and Glutathione Changes in Ascites Daltons Lymphoma Cells: In silico Analysis of Rutin Interactions with Some Antiapoptotic and Glutathione-related Proteins |
| 250 ## - EDITION STATEMENT |
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| Volume, Issue number |
Vol. 81 (04) |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
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| Place of publication, distribution, etc. |
Mumbai |
| Name of publisher, distributor, etc. |
Indian Journal of Pharmaceutical Science |
| Year |
2019 |
| 300 ## - PHYSICAL DESCRIPTION |
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| Pagination |
720-728p. |
| 520 ## - SUMMARY, ETC. |
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| Summary, etc. |
Rutin-induced changes in apoptosis and reduced glutathione levels was studied in murine ascites Dalton’s lymphoma cells under different treatment conditions followed by the binding affinity of rutin and cis-diamminedichloroplatinum (II) with two antiapoptotic proteins and two glutathione-related enzymes was examined through molecular docking analysis. Rutin, as well as cis-diamminedichloroplatinum (II) induced apoptosis and a decrease in reduced glutathione level in Dalton’s lymphoma cells. The molecular interactions of rutin, cis-diamminedichloroplatinum (II) and a known inhibitor of the protein/enzyme showed that the binding free energies (ΔG) with antiapoptotic proteins, Bcl-xL and c-FLIP, and glutathione-related enzymes such as glutathione S-transferase and glutathione reductase were closer and comparable, which might suggest inhibitory potential of rutin on these proteins/enzymes and could play a role in its anticancer activity. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| 9 (RLIN) |
4639 |
| Topical term or geographic name entry element |
PHARMACEUTICS |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| 9 (RLIN) |
7238 |
| Co-Author |
Banerjee, S. |
| 773 0# - HOST ITEM ENTRY |
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| Title |
Indian journal of pharmaceutical sciences |
| International Standard Serial Number |
0250-474X |
| Place, publisher, and date of publication |
New Delhi Indian Pharmaceutical Association |
| 856 ## - ELECTRONIC LOCATION AND ACCESS |
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| Link text |
Click Here to Explore Digital Copy |
| URL |
http://www.ijpsonline.com/articles/rutinmediated-apoptosis-and-glutathione-changes-in-ascites-daltons-lymphoma-cells-iin-silicoi-analysis-of-rutin-interactions-with-3673.html |
| Public note |
Click here |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
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| Source of classification or shelving scheme |
|
| Koha item type |
Articles Abstract Database |
