000 -LEADER |
fixed length control field |
a |
003 - CONTROL NUMBER IDENTIFIER |
control field |
OSt |
005 - DATE AND TIME OF LATEST TRANSACTION |
control field |
20191221120218.0 |
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
fixed length control field |
191221b xxu||||| |||| 00| 0 eng d |
040 ## - CATALOGING SOURCE |
Original cataloging agency |
AIKTC-KRRC |
Transcribing agency |
AIKTC-KRRC |
100 ## - MAIN ENTRY--PERSONAL NAME |
9 (RLIN) |
11337 |
Author |
Tascon-otero, Estefania |
245 ## - TITLE STATEMENT |
Title |
Enhancement of the Dissolution Rate of Indomethacin by Solid Dispersions in Low-substituted Hydroxypropyl Cellulose |
250 ## - EDITION STATEMENT |
Volume, Issue number |
Vol. 81 (05) |
260 ## - PUBLICATION, DISTRIBUTION, ETC. |
Place of publication, distribution, etc. |
Mumbai |
Name of publisher, distributor, etc. |
Indian Journal of Pharmaceutical Science |
Year |
2019 |
300 ## - PHYSICAL DESCRIPTION |
Pagination |
824-833p. |
520 ## - SUMMARY, ETC. |
Summary, etc. |
In the present study, new indomethacin formulations were developed in order to enhance the indomethacin dissolution rate by preparing solid dispersions using the freeze-drying method. The degree of alterations in the crystallinity of indomethacin was assessed according to the preparation method and by the addition of low-substituted hydroxypropyl cellulose. Solid dispersions improved the dissolution rate of indomethacin. Combined use of scanning electron microscopy, X-ray powder diffraction and differential scanning calorimetry revealed the basis of the increase in dissolution rate of indomethacin when formulated as low-substituted hydroxypropyl cellulose solid dispersions. |
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
9 (RLIN) |
4639 |
Topical term or geographic name entry element |
PHARMACEUTICS |
700 ## - ADDED ENTRY--PERSONAL NAME |
9 (RLIN) |
11338 |
Co-Author |
Torre-Iglesias, Paloma |
773 0# - HOST ITEM ENTRY |
Title |
Indian journal of pharmaceutical sciences |
International Standard Serial Number |
0250-474X |
Place, publisher, and date of publication |
New Delhi Indian Pharmaceutical Association |
856 ## - ELECTRONIC LOCATION AND ACCESS |
URL |
http://www.ijpsonline.com/articles/enhancement-of-the-dissolution-rate-of-indomethacin-by-solid-dispersions-in-lowsubstituted-hydroxypropyl-cellulose-3696.html |
Link text |
Click here |
942 ## - ADDED ENTRY ELEMENTS (KOHA) |
Source of classification or shelving scheme |
|
Koha item type |
Articles Abstract Database |