| 000 -LEADER |
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| fixed length control field |
a |
| 003 - CONTROL NUMBER IDENTIFIER |
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| control field |
OSt |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
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| control field |
20200110122257.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
200110b xxu||||| |||| 00| 0 eng d |
| 040 ## - CATALOGING SOURCE |
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| Original cataloging agency |
AIKTC-KRRC |
| Transcribing agency |
AIKTC-KRRC |
| 100 ## - MAIN ENTRY--PERSONAL NAME |
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| 9 (RLIN) |
11645 |
| Author |
Karale, S. |
| 245 ## - TITLE STATEMENT |
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| Title |
Anti-inflammatory and antinociceptive activities of gymnemic acid in wistar rats |
| 250 ## - EDITION STATEMENT |
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| Volume, Issue number |
Vol.56(2), Feb |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
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| Place of publication, distribution, etc. |
Mumbai |
| Name of publisher, distributor, etc. |
Indian Drug Manufacture's Association - IDMA |
| Year |
2019 |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Pagination |
57-63p. |
| 520 ## - SUMMARY, ETC. |
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| Summary, etc. |
The present study was aimed to evaluate anti-inflammatory and antinociceptive activities of gymnemic acid (GA) in Wistar rats. The different doses of GA were tested for their anti-inflammatory in carrageenaninduced rat paw oedema animal model by using buzzer assisted plethysmograph and antinociceptive activities by tail immersion screening model in organ bath, respectively. It was found that GA at the dose of 100 and 150 mg/kg, p.o, significantly (P<0.01) inhibited the carrageenan-induced rat paw edema and significantly (P<0.01) suppressed the threshold pain of rat by tail immersion method. GA showed significant anti-inflammatory and antinociceptive activities at 2nd and 3rd hr. Further, to know the possible mode of action, we evaluated the effect of GA on castor oil-induced diarrhea. The frequency of stool formation was reduced due to GA in castor oil-induced diarrhea, perhaps due to suppression of prostaglandin, suggesting anti-inflammatory and antinociceptive activities. The current findings demonstrate that the administration of GA at the dose of 100 and 150 mg/kg, by oral route produced significant anti-inflammatory and antinociceptive effects in Wistar rats. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| 9 (RLIN) |
4639 |
| Topical term or geographic name entry element |
PHARMACEUTICS |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| 9 (RLIN) |
11646 |
| Co-Author |
Kulkarni, V. H. |
| 773 0# - HOST ITEM ENTRY |
|---|
| Place, publisher, and date of publication |
Mumbai Indian Drug Manufactures Association |
| Title |
Indian drugs |
| 856 ## - ELECTRONIC LOCATION AND ACCESS |
|---|
| URL |
https://www.indiandrugsonline.org/issuesarticle-details?id=ODk5 |
| Link text |
Click here |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
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| Source of classification or shelving scheme |
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| Koha item type |
Articles Abstract Database |
