000 -LEADER |
fixed length control field |
a |
003 - CONTROL NUMBER IDENTIFIER |
control field |
OSt |
005 - DATE AND TIME OF LATEST TRANSACTION |
control field |
20200113114355.0 |
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
fixed length control field |
200113b xxu||||| |||| 00| 0 eng d |
040 ## - CATALOGING SOURCE |
Original cataloging agency |
AIKTC-KRRC |
Transcribing agency |
AIKTC-KRRC |
100 ## - MAIN ENTRY--PERSONAL NAME |
9 (RLIN) |
11658 |
Author |
Navale, Govind |
245 ## - TITLE STATEMENT |
Title |
Membrane Stabilization assay for Anti-inflammatory activity yields misleading results for samples containing traces of Methanol |
250 ## - EDITION STATEMENT |
Volume, Issue number |
Vol.9(3), Jul-Sep |
260 ## - PUBLICATION, DISTRIBUTION, ETC. |
Place of publication, distribution, etc. |
Raipur |
Name of publisher, distributor, etc. |
Asian Pharma Press |
Year |
2019 |
300 ## - PHYSICAL DESCRIPTION |
Pagination |
169-171p. |
520 ## - SUMMARY, ETC. |
Summary, etc. |
There is an increased in the reports on erythrocyte haemolysis assay being used as a simple and rapid tool for screening of drugs and phytochemicals for anti-inflammatory activity. However, in case of hydroalchoholic extracts, there is a possibility of the trace amounts of methanol retained even after drying. These traces are not acconted in the assay units. The present study was designated to substantiate the effects of low concentrations of methanol on the heat induced haemolysis. It was observed that the presence of methanol at concentrations as low as 0.1 ?l/ml exert significant membrane stabilizing activity. Thus, this assay may give misleading results if the test drug solution contains even slighest amount of methanol. Therefore, Present study suggested that the heat-induced erythrocyte haemolysis assay is not suitable for testing membrane stabilizing and anti-inflammmatory activity of the test samples containing methanol. |
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
9 (RLIN) |
4639 |
Topical term or geographic name entry element |
PHARMACEUTICS |
700 ## - ADDED ENTRY--PERSONAL NAME |
9 (RLIN) |
11659 |
Co-Author |
Patil, Dipak D. |
773 0# - HOST ITEM ENTRY |
Title |
Asian journal of pharmaceutical research |
International Standard Serial Number |
2231-5683 |
Place, publisher, and date of publication |
Raipur Asian Pharma Press |
856 ## - ELECTRONIC LOCATION AND ACCESS |
URL |
https://asianjpr.com/AbstractView.aspx?PID=2019-9-3-5 |
Link text |
Click here |
942 ## - ADDED ENTRY ELEMENTS (KOHA) |
Source of classification or shelving scheme |
|
Koha item type |
Articles Abstract Database |