PHYSICOCHEMICAL CHARACTERISTICS OF RASAMANIKYA -AN AYURVEDIC ARSENICAL FORMULATION (Record no. 11191)

000 -LEADER
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003 - CONTROL NUMBER IDENTIFIER
control field OSt
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20200212113153.0
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 200212b xxu||||| |||| 00| 0 eng d
040 ## - CATALOGING SOURCE
Original cataloging agency AIKTC-KRRC
Transcribing agency AIKTC-KRRC
100 ## - MAIN ENTRY--PERSONAL NAME
9 (RLIN) 12142
Author Singh, Arjun
245 ## - TITLE STATEMENT
Title PHYSICOCHEMICAL CHARACTERISTICS OF RASAMANIKYA -AN AYURVEDIC ARSENICAL FORMULATION
250 ## - EDITION STATEMENT
Volume, Issue number Vol.11(5)
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Place of publication, distribution, etc. M P
Name of publisher, distributor, etc. Innovare Academic Sciences Pvt Ltd
Year 2019
300 ## - PHYSICAL DESCRIPTION
Pagination 31-36p.
520 ## - SUMMARY, ETC.
Summary, etc. Objective:
The objective
of this study was standardization and Chemical char
acterization of
rasamanikya
prepared as per standard operating
procedures (SOP) mentioned in the classical text.
Methods:
Rasamanikya
was prepared by putting
churnodaka
shodhita haratala
(Orpiment-As
2
S
3
) between two
abhraka
(white mica) sheets which
are heated for a while to obtain a red colored fini
shed product. The Ayurvedic specifications for the
analysis of
rasamanikya
were performed
through qualitative and quantitative analysis. Phys
icochemical analysis, assay of elements by atomic a
bsorption spectrometer (AAS) and inductively
coupled plasma-atomic emission spectrometry (ICP-AE
S) were carried out and some other tests such as x-
ray diffraction (XRD), x-ray photoelectron
spectroscopy (XPS) and energy dispersive x-ray anal
yzer (EDAX) were also performed to ensure the quali
ty of the drug.
Results:
In the finished drug Arsenic and Sulphur are presen
t in the form of As
4
S
4
, As
2
S
3
, As
2
S
5
. On the basis of XPS survey scans, scanning electr
on
microscopy-energy dispersive x-ray analyzer (SEM-ED
AX) and carbon, hydrogen, nitrogen, sulphur (CHNS) a
nalysis the Arsenic to Sulphur (As to S)
ratio is thus standardized as 39-47: 53-61. In addi
tion to this powder, XRD shows a major conversion i
nto an amorphous phase.
Conclusion:
The results could be used to lay down a new set of
pharmacopoeial standards for the preparation of
rasamanikya
for getting optimal
efficacy of medicine. Therefore, the information wi
ll help the Scientists and Researchers to build com
prehensive standards, to screen the
compounds responsible for different bioactivities,
and to elucidate the molecular mechanism of action.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
9 (RLIN) 4639
Topical term or geographic name entry element PHARMACEUTICS
700 ## - ADDED ENTRY--PERSONAL NAME
9 (RLIN) 12143
Co-Author Ota, Sarada
773 0# - HOST ITEM ENTRY
International Standard Serial Number 2656-0097
Place, publisher, and date of publication Bhopal Innovare Academic Sciences Pvt Ltd
Title International journal of pharmacy and pharmaceutical science
856 ## - ELECTRONIC LOCATION AND ACCESS
URL https://innovareacademics.in/journals/index.php/ijpps/article/view/29429/19861
Link text Click here
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme
Koha item type Articles Abstract Database
Holdings
Withdrawn status Lost status Source of classification or shelving scheme Damaged status Not for loan Permanent Location Current Location Shelving location Date acquired Barcode Date last seen Price effective from Koha item type
          School of Pharmacy School of Pharmacy Archieval Section 2020-02-12 2020924 2020-02-12 2020-02-12 Articles Abstract Database
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