ANTIHYPERLIPIDEMIC EFFECT OF ETHANOLIC SEED EXTRACT OF CANAVALIA ENSIFORMIS ( L) IN HIGH FAT DIET -STREPTOZOTOCIN INDUCED RATS (Record no. 11213)

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003 - CONTROL NUMBER IDENTIFIER
control field OSt
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20200213120636.0
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 200213b xxu||||| |||| 00| 0 eng d
040 ## - CATALOGING SOURCE
Original cataloging agency AIKTC-KRRC
Transcribing agency AIKTC-KRRC
100 ## - MAIN ENTRY--PERSONAL NAME
9 (RLIN) 12184
Author Anitha, K.
245 ## - TITLE STATEMENT
Title ANTIHYPERLIPIDEMIC EFFECT OF ETHANOLIC SEED EXTRACT OF CANAVALIA ENSIFORMIS ( L) IN HIGH FAT DIET -STREPTOZOTOCIN INDUCED RATS
250 ## - EDITION STATEMENT
Volume, Issue number Vol.11(1)
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Place of publication, distribution, etc. M P
Name of publisher, distributor, etc. Innovare Academic Sciences Pvt Ltd
Year 2019
300 ## - PHYSICAL DESCRIPTION
Pagination 99-102p.
520 ## - SUMMARY, ETC.
Summary, etc. Objective:
It was investigated to enlighten the phytochemical screening and
antihyperlipidemic
activity
of seeds of
Canavalia ensiformis (L.)
in High
fat diet Streptozotocin
-induced
diabetic rats.
Method
s:
The
e
thanolic seed extract of
Canavalia ensiformis
(EECE) at a dose of 40
0 mg
/kg and 200 mg/kg was administered to diabetic r
ats.
Simvastatin (
4 mg/kg) is used as
a standard
drug.
Result
s:
The statistics
were
assessed by using one way ANOVA followed by Dunnet’s multiple comparison tests. To unfold the mechanism we
studied
all the biochemical parameters like
Total cholesterol (T
C), Triglycerides
(TG),
high
-density
lipoproteins
(HDL
),
low
-density
lipoproteins
(LDL
) and histopathological examination of Liver tissue section. The ethanolic extracts of seeds of
Canavalia ensiformis
showed significant reduce
of
the
level
of cholesterol
, triglycerides, LDL, VLDL and
a significant
increase in the serum level of HDL at 40
0 mg
/kg rather than 200 mg/kg.
Conclusio
n:
Further the characterization and isolation of the constituents could be done to know the exact mechanism of hyperlipidemic ac
tiv
ity.
Statistical analysis of this screening method conforms
that the proposed method is
appropriate
and it can be useful, gives the basic idea to the
researcher who is working in
an
area
like Antihyperlipidemic activity.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
9 (RLIN) 4639
Topical term or geographic name entry element PHARMACEUTICS
700 ## - ADDED ENTRY--PERSONAL NAME
9 (RLIN) 12185
Co-Author Puthalapattu, Ravikumar Yashoda
773 0# - HOST ITEM ENTRY
Place, publisher, and date of publication Bhopal Innovare Academic Sciences Pvt Ltd
International Standard Serial Number 2656-0097
Title International journal of pharmacy and pharmaceutical science
856 ## - ELECTRONIC LOCATION AND ACCESS
URL https://innovareacademics.in/journals/index.php/ijpps/article/view/28961/16555
Link text Click here
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme
Koha item type Articles Abstract Database
Holdings
Withdrawn status Lost status Source of classification or shelving scheme Damaged status Not for loan Permanent Location Current Location Shelving location Date acquired Barcode Date last seen Price effective from Koha item type
          School of Pharmacy School of Pharmacy Archieval Section 2020-02-13 2020943 2020-02-13 2020-02-13 Articles Abstract Database
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