IN VITRO SUSCEPTIBILITY OF ISOLATED SHIGELLA FLEXNERI AND SHIGELLA DYSENTERIAE TO THE ETHANOLIC EXTRACTS OF TRACHYSPERMUM AMMI AND PEGANUM HARMALA (Record no. 11214)

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control field OSt
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20200213121044.0
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 200213b xxu||||| |||| 00| 0 eng d
040 ## - CATALOGING SOURCE
Original cataloging agency AIKTC-KRRC
Transcribing agency AIKTC-KRRC
100 ## - MAIN ENTRY--PERSONAL NAME
9 (RLIN) 12186
Author Ibrahim Siddig Hamid
245 ## - TITLE STATEMENT
Title IN VITRO SUSCEPTIBILITY OF ISOLATED SHIGELLA FLEXNERI AND SHIGELLA DYSENTERIAE TO THE ETHANOLIC EXTRACTS OF TRACHYSPERMUM AMMI AND PEGANUM HARMALA
250 ## - EDITION STATEMENT
Volume, Issue number Vol.11(1)
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Place of publication, distribution, etc. M P
Name of publisher, distributor, etc. Innovare Academic Sciences Pvt Ltd
Year 2019
300 ## - PHYSICAL DESCRIPTION
Pagination 103-106p.
520 ## - SUMMARY, ETC.
Summary, etc. Objective:
This study represents the first attempt to investigate the antimicrobial activity of
Peganum
harmala
,
and
Trachyspermum
ammi
seeds
extract
against the isolated bacillary dysentery
-causing
microorganisms.
Method
s:
T.
ammi
and
P.
harmala
were extracted by 96% ethanol using Soxhlet apparatus. The extracts were screened for their phytochemical
constituents. Their antimicrobial activity against
the isolated
dysentery
-causing
microorganisms was evaluated using the agar diffusion method.
Result
s:
The antimicrobial activity result showed that, the two isolated bacteria,
Shigella flexneri
,
and
Shigella dysenteriae
were found to be
sensitive to the extract of
T.
ammi
seed with
inhibition zones up to 2
5 mm
, compared to the inhibition zone of 2
0 mm
produced by Gentamycin
standard drug
, this is mainly due to the presence of the different phytochemical in the extract such as tannin, flavonoids, terpenoids whi
ch are well
known for th
eir antimicrobial effects
. The two isolated bacteria were
found to be insensitive (zero mm) to
P.
harmala
extract,
Amoxicillin
, and
Amoclan (Amoxicillin
+clavulanic acid) standard
drugs,
this is due to the fact that, the phytochemicals constituents of
P.
harmala
possess
the
antagonistic effect to
each
other’s
. Addition t
o;
these bacteria became resistant to both Amoxicillin and Amoclan.
Conclusio
n:
From the results it concludes,
T.
ammi
seeds extract had a considerable level of antimicrobial activity against bacillary dysentery
-
causing
microorganisms resistant to Amoxicillin and Amoxicillin
+clavulanic acid drugs.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
9 (RLIN) 4639
Topical term or geographic name entry element PHARMACEUTICS
700 ## - ADDED ENTRY--PERSONAL NAME
9 (RLIN) 12187
Co-Author Eltayeb, Ikram Mohamed
773 0# - HOST ITEM ENTRY
Place, publisher, and date of publication Bhopal Innovare Academic Sciences Pvt Ltd
International Standard Serial Number 2656-0097
Title International journal of pharmacy and pharmaceutical science
856 ## - ELECTRONIC LOCATION AND ACCESS
URL https://innovareacademics.in/journals/index.php/ijpps/article/view/29411/16556
Link text Click here
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme
Koha item type Articles Abstract Database
Holdings
Withdrawn status Lost status Source of classification or shelving scheme Damaged status Not for loan Permanent Location Current Location Shelving location Date acquired Barcode Date last seen Price effective from Koha item type
          School of Pharmacy School of Pharmacy Archieval Section 2020-02-13 2020944 2020-02-13 2020-02-13 Articles Abstract Database
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