| 000 -LEADER |
|---|
| fixed length control field |
a |
| 003 - CONTROL NUMBER IDENTIFIER |
|---|
| control field |
OSt |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
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| control field |
20200215100310.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
200215b xxu||||| |||| 00| 0 eng d |
| 040 ## - CATALOGING SOURCE |
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| Original cataloging agency |
AIKTC-KRRC |
| Transcribing agency |
AIKTC-KRRC |
| 100 ## - MAIN ENTRY--PERSONAL NAME |
|---|
| 9 (RLIN) |
12306 |
| Author |
Pushpa Kumari, K. |
| 245 ## - TITLE STATEMENT |
|---|
| Title |
STABILITY INDICATING UPLC METHOD FOR SIMULTANEOUS ESTIMATION OF EMTRICITABINE, BICTEGRAVIR AND TENOFOVIR ALAFeNAMIDE |
| 250 ## - EDITION STATEMENT |
|---|
| Volume, Issue number |
Vol.57(01), Jan |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
|---|
| Place of publication, distribution, etc. |
Mum bai |
| Name of publisher, distributor, etc. |
Indian Drug Manufacture's Association - IDMA |
| Year |
2020 |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Pagination |
44-50p. |
| 520 ## - SUMMARY, ETC. |
|---|
| Summary, etc. |
A simple, specific, precise and robust method for the estimation of emtricitabine, bictegravir and tenofovir alafenamide in the presence of impurities was developed and validated. The separation was performed on Aquity UPLC system with SB C8 50 x 2.1 mm, 1.7μ column under isocratic elution mode. The components were eluted using 0.01 N phosphate buffer and acetonitrile in the ratio of 50:50 V/V and detected at UV wavelength of 272 nm. The retention times were found to be 1.017 min, 1.484 min and 1.864 min for emtricitabine, bictegravir and tenofovir alafenamide, respectively. The developed method was validated as per ICH guidelines. The method was stable and specific and when the sample was stressed under different conditions (acid, base, peroxide, photolytic, neutral, no interference of degradants were observed. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| 9 (RLIN) |
4639 |
| Topical term or geographic name entry element |
PHARMACEUTICS |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
|---|
| 9 (RLIN) |
12307 |
| Co-Author |
Gowri Sankar, D. |
| 773 0# - HOST ITEM ENTRY |
|---|
| Place, publisher, and date of publication |
Mumbai Indian Drug Manufactures Association |
| Title |
Indian drugs |
| 856 ## - ELECTRONIC LOCATION AND ACCESS |
|---|
| URL |
https://www.indiandrugsonline.org/issuesarticle-details?id=MTAxMw== |
| Link text |
Click here |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
|---|
| Source of classification or shelving scheme |
|
| Koha item type |
Articles Abstract Database |
