Impact of Smoking and Alcohol Consumption on Oxidative Status in Male Infertility and Sperm Quality (Record no. 13773)

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040 ## - CATALOGING SOURCE
Original cataloging agency AIKTC-KRRC
Transcribing agency AIKTC-KRRC
100 ## - MAIN ENTRY--PERSONAL NAME
9 (RLIN) 12691
Author Ramgir, Shalaka S.
245 ## - TITLE STATEMENT
Title Impact of Smoking and Alcohol Consumption on Oxidative Status in Male Infertility and Sperm Quality
250 ## - EDITION STATEMENT
Volume, Issue number Vol.81(5), Sep-Oct
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Place of publication, distribution, etc. Mumbai
Name of publisher, distributor, etc. Indian Journal of Pharmaceutical Science
Year 2019
300 ## - PHYSICAL DESCRIPTION
Pagination 933-945p.
520 ## - SUMMARY, ETC.
Summary, etc. The most common unhealthy lifestyle factors like cigarette smoking and drinking alcohol have controversial reports on how these impact male fertility. The present study assessed the potential effects of these habits on sperm quality, male reproductive hormones, and blood plasma oxidative profile in 133 infertile men with 124 fertile, healthy controls. Among the participants, 28 (10.8 %), 29 (11.2 %), 33 (12.8 %), 34 (13.2 %) fertile men were non-alcoholics and non-smokers (total abstainers), smokers, alcohol drinkers, and smokers plus alcohol drinkers, respectively. On the other hand, 32 (12.4 %), 30 (11.6 %), 34 (13.2 %), 37 (14.3 %) infertile men were total abstainers, smokers, alcohol drinkers, and smokers plus alcohol drinkers, respectively. The conventional sperm parameters and reproductive hormone levels were found to be significantly different in the subsets of infertile men than those of fertile men (p<0.001). In these subsets of infertile men, blood plasma malondialdehyde, nitric oxide concentrations were significantly higher and superoxide dismutase, reduced glutathione activities were significantly lower when compared to fertile men and infertile men total abstainers group (p<0.001). In infertile subjects, particularly smoking-alcohol drinking group was more affected than only smoking or alcohol drinking groups. Furthermore, these oxidative markers were correlated with sperm concentration, motility, and morphology, except nitric oxide concentration, which was only associated with sperm motility. These findings highlighted that blood plasma antioxidants are as efficient as seminal plasma antioxidants in male fertility evaluation.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
9 (RLIN) 4639
Topical term or geographic name entry element PHARMACEUTICS
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9 (RLIN) 12692
Co-Author Abilash, V. G.
773 0# - HOST ITEM ENTRY
International Standard Serial Number 0250-474X
Place, publisher, and date of publication New Delhi Indian Pharmaceutical Association
Title Indian journal of pharmaceutical sciences
856 ## - ELECTRONIC LOCATION AND ACCESS
URL https://www.ijpsonline.com/articles/impact-of-smoking-and-alcohol-consumption-on-oxidative-status-in-male-infertility-and-sperm-quality.pdf
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          School of Pharmacy School of Pharmacy Archieval Section 2020-12-07 2020-2021118 2020-12-07 2020-12-07 Articles Abstract Database
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