| 000 -LEADER |
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a |
| 003 - CONTROL NUMBER IDENTIFIER |
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OSt |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
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20201221110843.0 |
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201221b xxu||||| |||| 00| 0 eng d |
| 040 ## - CATALOGING SOURCE |
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AIKTC-KRRC |
| Transcribing agency |
AIKTC-KRRC |
| 100 ## - MAIN ENTRY--PERSONAL NAME |
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| 9 (RLIN) |
12824 |
| Author |
Smerikarova, M. |
| 245 ## - TITLE STATEMENT |
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| Title |
Development and Validation of a RP-HPLC Method to Quantify Amoxicillin, Tinidazole, Esomeprazole and Lan-soprazole in a Mixture |
| 250 ## - EDITION STATEMENT |
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| Volume, Issue number |
Vol.81(6), Nov-Dec |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
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| Place of publication, distribution, etc. |
Mumbai |
| Name of publisher, distributor, etc. |
Indian Journal of Pharmaceutical Science |
| Year |
2019 |
| 300 ## - PHYSICAL DESCRIPTION |
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| Pagination |
1122-1127p. |
| 520 ## - SUMMARY, ETC. |
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| Summary, etc. |
Present investigation dealt with the developing of a reversed phase-high performance liquid chromatographic method for determination of amoxicillin, tinidazole, esomeprazole and lansoprazole in pure state and as a mixture. Chromatographic separation was performed isocratically on a LiChrospher® 100 RP-18 column. The flow rate was 1.0 ml/min and the detector was set at 280 nm. The method was developed at ambient temperature with a mobile phase, 40:60 v/v acetonitrile and phosphate buffer (0.001 M, pH 7.6). The selected conditions were applicable for separating amoxicillin, tinidazole, esomeprazole and lansoprazole with retention times 3.11, 5.37, 11.71 and 17.67 min, respectively. The method was validated for parameters including linearity, selectivity, precision and accuracy, limit of detection and limit of quantitation. Linear calibration curves were obtained in the concentration range of 250.0-2000.0, 125-1000.0, 5.0-40.0 and 7.5-60.0 μg/ml for amoxicillin, tinidazole, esomeprazole and lansoprazole, respectively. The proposed method was found to be effective and could be used for quantification of these drugs in routine quality control practice. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| 9 (RLIN) |
4639 |
| Topical term or geographic name entry element |
PHARMACEUTICS |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| 9 (RLIN) |
12825 |
| Co-Author |
Bozhanov, S. |
| 773 0# - HOST ITEM ENTRY |
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| Title |
Indian journal of pharmaceutical sciences |
| Place, publisher, and date of publication |
New Delhi |
| 856 ## - ELECTRONIC LOCATION AND ACCESS |
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| URL |
https://www.ijpsonline.com/articles/development-and-validation-of-a-rphplc-method-to-quantify-amoxicillin-tinidazole-esomeprazole-and-lansoprazole-in-a-mixt.pdf |
| Link text |
Click here |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
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| Source of classification or shelving scheme |
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| Koha item type |
Articles Abstract Database |
