Evaluation of the hypoglycemic activity of aqueous and alcoholic extracts leaves of Leucas indica var. nagalapuramiana in normoglycemic and hyperglycemic rats (Record no. 15646)

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fixed length control field 211220b xxu||||| |||| 00| 0 eng d
040 ## - CATALOGING SOURCE
Original cataloging agency AIKTC-KRRC
Transcribing agency AIKTC-KRRC
100 ## - MAIN ENTRY--PERSONAL NAME
9 (RLIN) 14884
Author Rani, Palli Subha
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Title Evaluation of the hypoglycemic activity of aqueous and alcoholic extracts leaves of Leucas indica var. nagalapuramiana in normoglycemic and hyperglycemic rats
250 ## - EDITION STATEMENT
Volume, Issue number Vol.15(3), Jul-Sept
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Place of publication, distribution, etc. Mandsaur
Name of publisher, distributor, etc. B.R. Nahata Smriti Sansthan
Year 2021
300 ## - PHYSICAL DESCRIPTION
Pagination 243-248p.
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Summary, etc. Background: Plants and their bioactive elements are used to treat diabetes mellitus, particularly in regions where provision to traditional allopathy is limited. There are several reports on the antidiabetic activity of Leucas spp. Objective: The present work was aimed for investigation of antidiabetic buy watson soma online effect of aqueous and alcoholic extracts of Leucas indica var. nagalapuramiana leaves on normoglycemic and streptozotocin (STZ)-induced hyperglycemic rats, and their effects were compared with standard oral hypoglycemic drug, tolbutamide (40 mg/kg). Methods: Animals weighing 180–200 g were selected for the study and were performed at three dose levels 100, 200, and 400 mg/kg of aqueous and ethanolic extracts in normoglycemic and STZ-induced hyperglycemic rats. Blood glucose levels (BGLs) were monitored at 1, 2, 4, 8, 16, and 24 h post-administration using glucometer. The experimental results were analyzed using ANNOVA followed by Turkey’s post hoc test to determine the statistical significance among treatment groups. Results: The results showed that at all time periods, no statistically significant difference in BGLs was seen when buy soma online next day delivery groups treated with varying doses of the extracts were compared to each other and to the standard treatment group. However, a significantly (P < 0.05) high percentage glucose reduction was observed with 400 mg/kg of aqueous and alcoholic extracts in normoglycemic rats and 400 mg/kg of alcoholic extracts in hyperglycemic rats, and is comparable to standard, tolbutamide (40 mg/kg).
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
9 (RLIN) 4774
Topical term or geographic name entry element PHARMACOLOGY
700 ## - ADDED ENTRY--PERSONAL NAME
9 (RLIN) 14885
Co-Author Rao, P. Rajeswara
773 0# - HOST ITEM ENTRY
Place, publisher, and date of publication Mandsaur B.R. Nahata Smriti Sansthan
Title International journal of green pharmacy
856 ## - ELECTRONIC LOCATION AND ACCESS
URL http://greenpharmacy.info/index.php/ijgp/article/view/3151
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          School of Pharmacy School of Pharmacy Archieval Section 2021-12-20 2021-2022464 2021-12-20 2021-12-20 Articles Abstract Database
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