studies on the therapeutic potentials of Datura metel L. unripen fruits (Record no. 15648)

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fixed length control field a
003 - CONTROL NUMBER IDENTIFIER
control field OSt
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20211220155301.0
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 211220b xxu||||| |||| 00| 0 eng d
040 ## - CATALOGING SOURCE
Original cataloging agency AIKTC-KRRC
Transcribing agency AIKTC-KRRC
100 ## - MAIN ENTRY--PERSONAL NAME
9 (RLIN) 14888
Author Bharathajothi, P.
245 ## - TITLE STATEMENT
Title studies on the therapeutic potentials of Datura metel L. unripen fruits
250 ## - EDITION STATEMENT
Volume, Issue number Vol. 15(3), Jul-Sept
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Place of publication, distribution, etc. Mandsaur
Name of publisher, distributor, etc. B.R. Nahata Smriti Sansthan
Year 2021
300 ## - PHYSICAL DESCRIPTION
Pagination 259-270p.
520 ## - SUMMARY, ETC.
Summary, etc. Introduction: Datura metel L. is a medicinal plant whose leaves and seeds are widely used in herbal medicine as anaesthetic, antispasmodic, antitussive, bronchodilator and as hallucinogenic. Materials and Methods how much does tramadol cost: Qualitative phytochemical analysis was performed to detect the presence of phytochemical constituents in a formulated Umaththankai parpam using a common plant Datura metel L with Ocimum sanctum leaves and sulphur. Antibacterial and antifungal analysis were carried out to determine its therapeutic potentials. The phytochemical compounds present in Umaththankai parpam was identified by GC-MS analysis with their molecular weight (MW), retention time (RT), concentration (peak area %), Molecular formula (MF). Results: The qualitative phytochemical analysis revealed the presence of various secondary metabolites and found to be containing alkaloids, flavonoids, saponins, fixed oils, tannin, phenols and glycosides; while protein, amino acid, steroids and terpenoids were found to be absent. The data showed that alkaloids, glycosides and flavonoids were found as strong positive than other metabolites. The crude extract has antibacterial activity against the Gram negative bacteria such as Pseudomonas aeruginosa and Escherichia coli and the Gram positive bacteria Staphylococcus aureus and also the phytochemicals exhibited antifungal activity against three fungal species such as Candida albicans, Aspergillus niger which are causing secondary infections to COVID19 patients and Tricophyton rubrum. Totally 10 compounds were identified and the high peak area compounds in this sample cost of tramadol were n- Hexadececanoic acid (54.24%) and others were 9,12- Octadecadienoyl chloride (15.63%), 9,12- Octadecadienoic acid(12.97%), Z,E-2-Methyl-3,13-octadecadien-1-ol(12.96%), Hexadecanoic acid, 1-(hydroxymethyl)-1,2-ethanediyl ester (2.30) and the rest of the compounds showing short peak area like 6-Tetradecanol(0.71%), 9,12-Octadecadien-1-ol, (Z,Z)- (0.54%), Benzene, 1,2-dimethoxy-4-(1-propenyl)-(0.52%), Methyl 6-methyl heptanoate (0.07%) and (S)-3,4-Dimethylpentanol (0.06%). Discussion and Conclusions: The peak compound n-hexadecanoic acid is a known anti-inflammatory agent and which was well documented in seaweeds but surprisingly the same compound has been found in our novel formulation. The second peak compound was 9,12-octadecadienoic acid and which has been reported as an antimicrobial compound in a different source. The study has brought out a wonderful formulation with readily available plant resources with potential therapeutic compounds and proved to be a drug source.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
9 (RLIN) 4755
Topical term or geographic name entry element PHARMACOGNOSY
653 ## - Keywords
Keywords Antibacterial
653 ## - Keywords
Keywords Antifungal
653 ## - Keywords
Keywords Phytochemicals
700 ## - ADDED ENTRY--PERSONAL NAME
9 (RLIN) 14889
Co-Author Bhaaskaran, C.T.
773 0# - HOST ITEM ENTRY
Title International journal of green pharmacy
Place, publisher, and date of publication Mandsaur B.R. Nahata Smriti Sansthan
856 ## - ELECTRONIC LOCATION AND ACCESS
URL http://greenpharmacy.info/index.php/ijgp/article/view/3153
Link text Full Text
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme
Koha item type Articles Abstract Database
Holdings
Withdrawn status Lost status Source of classification or shelving scheme Damaged status Not for loan Permanent Location Current Location Shelving location Date acquired Barcode Date last seen Price effective from Koha item type
          School of Pharmacy School of Pharmacy Archieval Section 2021-12-20 2021-2022466 2021-12-20 2021-12-20 Articles Abstract Database
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