Disposal of Uranium and Thorium Entering the Human Digestive System before Reaching the Blood by Adsorption on Simethicone and Forming a Non-absorbable Compound: A Full in vitro Analysis (Record no. 15674)

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005 - DATE AND TIME OF LATEST TRANSACTION
control field 20211221142111.0
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040 ## - CATALOGING SOURCE
Original cataloging agency AIKTC-KRRC
Transcribing agency AIKTC-KRRC
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9 (RLIN) 14936
Author Mira, Hamed Ibrahim
245 ## - TITLE STATEMENT
Title Disposal of Uranium and Thorium Entering the Human Digestive System before Reaching the Blood by Adsorption on Simethicone and Forming a Non-absorbable Compound: A Full in vitro Analysis
250 ## - EDITION STATEMENT
Volume, Issue number Vol.55(1), Jan-Mar
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Place of publication, distribution, etc. Karnataka
Name of publisher, distributor, etc. Association of Pharmaceutical Teachers of India (APTI)
Year 2021
300 ## - PHYSICAL DESCRIPTION
Pagination 146-152p.
520 ## - SUMMARY, ETC.
Summary, etc. Introduction: This method was applied to form a non-absorbable complex with uranium and thorium swallowed with contaminated dust or other sources to get rid of them before absorption into the blood and discarded outside the body. A non-GIT absorbable simethicone was used in this method for the adsorption of uranium (VI) and thorium (IV) from a solution similar to the gastrointestinal tract pH medium. Materials and Methods: Accurately measured 9 mg of pure standard uranyl nitrate and simethicone emulsion in concentration range (100-300 mg) at 37±1°C for 20 min in pH ranges like the medium of the stomach and intestine then take the supernatant after centrifugation to make sure of decreasing of the concentration of uranium and thorium ions by ICP Mass Spectroscopy (ICP-MS). Results and Discussion: The data recorded for different total uranium and thorium concentrations reveal convergent behavior. Increasing simethicone concentration inside the safe dose shifts the sorption of uranium and thorium to 100 % of the total concentration, calculated t and F values were compared with the reference method and the proposed method was equally precise and accurate. Conclusion: The data indicate that the method can successfully be applied for the complete adsorption of uranium and thorium on simethicone from GIT before reaching the blood.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
9 (RLIN) 4639
Topical term or geographic name entry element PHARMACEUTICS
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9 (RLIN) 14937
Co-Author Abdalaty, Nashat Mohamed Alanwar
773 0# - HOST ITEM ENTRY
International Standard Serial Number 0019-5464
Title Indian journal of pharmaceutical education and research
Place, publisher, and date of publication Bengluru Association of Pharmaceutical Teachers of India (APTI)
856 ## - ELECTRONIC LOCATION AND ACCESS
URL https://www.ijper.org/sites/default/files/IndJPhaEdRes_55_1_146.pdf
Link text Click here
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme
Koha item type Articles Abstract Database
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          School of Pharmacy School of Pharmacy Archieval Section 2021-12-21 2021-2022494 2021-12-21 2021-12-21 Articles Abstract Database
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