In vitro and In vivo Evaluation of the Wound Healing Potential of the Extracts of Schinus molle L. (Anacardiaceae) Grown in Jordan (Record no. 15777)
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| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | OSt |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20211228103813.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 211228b xxu||||| |||| 00| 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | AIKTC-KRRC |
| Transcribing agency | AIKTC-KRRC |
| 100 ## - MAIN ENTRY--PERSONAL NAME | |
| 9 (RLIN) | 15128 |
| Author | ABOALHAIJA, NOUR |
| 245 ## - TITLE STATEMENT | |
| Title | In vitro and In vivo Evaluation of the Wound Healing Potential of the Extracts of Schinus molle L. (Anacardiaceae) Grown in Jordan |
| 250 ## - EDITION STATEMENT | |
| Volume, Issue number | Vol.83(2), March-April |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Mumbai |
| Name of publisher, distributor, etc. | Indian Journal of Pharmaceutical Science |
| Year | 2021 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Pagination | 261-270p. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | The aim of this study was to assess the wound healing potential of Schinus molle L. aqueous and ethanol extracts. First, the antimicrobial activity of Schinus molle extracts was tested against six microorganisms (Staphylococcus aureus, Escherichia coli , Pseudomonas aeruginosa , Staphylococcus epidermidis , Enterococcus faecalis and Citrobacter freundii) . The growth of Citrobacter freundii and Enterococcus faecalis was totally inhibited by the aqueous extract at the lowest tested concentration (1.56 mg/ml). Next, in vitro wound healing assays were performed using humanfibroblast cells’ proliferation and scratch tests. Based on the obtained promising results, the aqueous extracts were further tested in an in vivo excision wound model in rats. Animals were treated with a hydrogel formula enriched with the plant aqueous extract in two different concentrations (2 % and 5 %). Re-epithelialization, fibrosis and neovascularization of the epidermis and sub-epidermal cells in the regenerated tissue was observed, accompanied by an increase in the tensile strength of the skin of the rats treated with the plant aqueous extract when compared to the negative control group. Our results strongly support the use of Schinus molle aqueous extracts in topical formulations to promote wound healing. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| 9 (RLIN) | 4639 |
| Topical term or geographic name entry element | PHARMACEUTICS |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| 9 (RLIN) | 15131 |
| Co-Author | AFIFI, FATMA |
| 773 0# - HOST ITEM ENTRY | |
| Title | Indian journal of pharmaceutical sciences |
| Place, publisher, and date of publication | New Delhi |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| URL | https://www.ijpsonline.com/articles/emin-vitroem-and-emin-vivo-em-evaluation-of-the-wound-healing-potential-of-the-extracts-of-emschinus-molleem-l-anacardia.pdf |
| Link text | Click here |
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| Source of classification or shelving scheme | |
| Koha item type | Articles Abstract Database |
| Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Permanent Location | Current Location | Shelving location | Date acquired | Barcode | Date last seen | Price effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| School of Pharmacy | School of Pharmacy | Archieval Section | 2021-12-28 | 2021-2022596 | 2021-12-28 | 2021-12-28 | Articles Abstract Database |