Therapeutic effect of certain Indian medicinal compounds against the Corona Virus: An in-silico study (Record no. 15886)

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control field OSt
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20220101145826.0
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fixed length control field 220101b xxu||||| |||| 00| 0 eng d
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Original cataloging agency AIKTC-KRRC
Transcribing agency AIKTC-KRRC
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9 (RLIN) 15322
Author Nand, Sakshi
245 ## - TITLE STATEMENT
Title Therapeutic effect of certain Indian medicinal compounds against the Corona Virus: An in-silico study
250 ## - EDITION STATEMENT
Volume, Issue number Vol.11(3), July-Sep
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Place of publication, distribution, etc. Raipur
Name of publisher, distributor, etc. Asian Pharma Press
Year 2021
300 ## - PHYSICAL DESCRIPTION
Pagination 167-172p.
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Summary, etc. Introduction: Since Covid-19 has emerged as a pandemic, it has taken innumerable lives and caused havoc in the developing as well as developed countries. The health facilities throughout the world have taken a toll and to counter this some immediate alternative measures have to be taken. Utilization of the plant-based products from the Indian traditional medicine can be one such measure. Methods: NCBI, Pubchem and PDB databases were used to obtain the structures of the relevant protein targets and plant-based ligands. Apart from this, softwares such as Open Babel, UCSF Chimera, PatchDock and FireDock were used for the purpose of interconversion of file formats, visualization of the structures and docking respectively. Results: After the screening of 9 plant-based products against the 3 main protein targets (spike protein, hemagglutinin, nucleocapsid) of corona virus we found that glucoraphanin showed the best binding energy against spike protein (-51.44 KJ/mol), alpha amyrin showed the best binding energy against hemagglutinin (-31.76 KJ/mol) and beta-sitosterol showed best binding energy against nucleocapsid (-55.44 KJ/mol). Conclusion: This study would aid in the speedy recovery and better immune response of the corona virus infected patients.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
9 (RLIN) 4639
Topical term or geographic name entry element PHARMACEUTICS
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9 (RLIN) 15323
Co-Author Neelabh
773 0# - HOST ITEM ENTRY
Place, publisher, and date of publication Raipur Asian Pharma Press
International Standard Serial Number 2231-5683
Title Asian journal of pharmaceutical research
856 ## - ELECTRONIC LOCATION AND ACCESS
URL https://asianjpr.com/AbstractView.aspx?PID=2021-11-3-5
Link text Click here
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme
Koha item type Articles Abstract Database
Holdings
Withdrawn status Lost status Source of classification or shelving scheme Damaged status Not for loan Permanent Location Current Location Shelving location Date acquired Barcode Date last seen Price effective from Koha item type
          School of Pharmacy School of Pharmacy Archieval Section 2022-01-01 2022-0021 2022-01-01 2022-01-01 Articles Abstract Database
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