| 000 -LEADER |
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| fixed length control field |
a |
| 003 - CONTROL NUMBER IDENTIFIER |
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| control field |
OSt |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
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| control field |
20220106114648.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
220106b xxu||||| |||| 00| 0 eng d |
| 040 ## - CATALOGING SOURCE |
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| Original cataloging agency |
AIKTC-KRRC |
| Transcribing agency |
AIKTC-KRRC |
| 100 ## - MAIN ENTRY--PERSONAL NAME |
|---|
| 9 (RLIN) |
15360 |
| Author |
Khan, Hamid |
| 245 ## - TITLE STATEMENT |
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| Title |
Identification and characterization of degradation products of valsartan by UPLC/Q-TOF-MS technique |
| 250 ## - EDITION STATEMENT |
|---|
| Volume, Issue number |
Vol.11(1), Jan-Mar |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
|---|
| Place of publication, distribution, etc. |
Raipur |
| Name of publisher, distributor, etc. |
Asian Pharma Press |
| Year |
2021 |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Pagination |
1-5p. |
| 520 ## - SUMMARY, ETC. |
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| Summary, etc. |
UPLC/Q-TOF-MS (Ultra-performance liquid chromatographic/quadrupole time-of-flight mass spectrometric) technique has been applied for identification and characterization of degradation products of Valsartan. For identification of drugs, the Q-TOF mass spectrometer was operated in negative ionization mode and quantification was done using the MS/MS transitions at m/z 434.50 to 255.50. The chromatographic separation was achieved on Acquity UPLCTM BEH C18 (100.0 × 2.1 mm, 1.7µm) column using isocratic mobile phase consisting of acetonitrile-2mM ammonium acetate (50:50, v/v) at a flow rate of 0.25 mL/min. Drug was degraded when treated with acid, alkali and oxidative stress conditions but found stable in photolytic condition. Degradation products were identified and possible degradation mechanisms were established. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| 9 (RLIN) |
4639 |
| Topical term or geographic name entry element |
PHARMACEUTICS |
| 773 0# - HOST ITEM ENTRY |
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| International Standard Serial Number |
2231-5683 |
| Title |
Asian journal of pharmaceutical research |
| Place, publisher, and date of publication |
Raipur Asian Pharma Press |
| 856 ## - ELECTRONIC LOCATION AND ACCESS |
|---|
| URL |
https://asianjpr.com/AbstractView.aspx?PID=2021-11-1-1 |
| Link text |
Click here |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
|---|
| Source of classification or shelving scheme |
|
| Koha item type |
Articles Abstract Database |
