Evaluation of gastroprotective effects of methanol extract of tephrosia villosa against experimentally induced ulcers in wistar rats (Record no. 15996)
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control field | OSt |
005 - DATE AND TIME OF LATEST TRANSACTION | |
control field | 20220119115401.0 |
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fixed length control field | 220119b xxu||||| |||| 00| 0 eng d |
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Original cataloging agency | AIKTC-KRRC |
Transcribing agency | AIKTC-KRRC |
100 ## - MAIN ENTRY--PERSONAL NAME | |
9 (RLIN) | 15492 |
Author | Rawal, Pinkey |
245 ## - TITLE STATEMENT | |
Title | Evaluation of gastroprotective effects of methanol extract of tephrosia villosa against experimentally induced ulcers in wistar rats |
250 ## - EDITION STATEMENT | |
Volume, Issue number | Vol.13 (11) |
260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
Place of publication, distribution, etc. | Bhopal |
Name of publisher, distributor, etc. | Innovare Academic Sciences Pvt Ltd |
Year | 2021 |
300 ## - PHYSICAL DESCRIPTION | |
Pagination | 20-23p. |
520 ## - SUMMARY, ETC. | |
Summary, etc. | Objective: The present research work was designed to investigate the gastroprotective potentials of methanol extract of Tephrosia villosa. Methods: The aerial parts of Tephrosia villosa were dried under shade, powdered and deffated with petroleum ether and then marc leftover was subjected to methanol extraction using soxhlet apparatus using soxh-let apparatus. Antiulcer activity of methanol extract was determined against stress-induced and aspirin-induced ulcers in experimental animal models. The total number of ulcers formed, ulcer index, percentage inhibition, ulcerated area, protected area, pH and Total acidity were parameters in the study. Results: Methanol extract of Tephrosia villosa at medium (200 mg/kg) and high (200 mg/kg) could significantly (P<0.01) reduced the total number of ulcers formed, ulcer index, ulcerated area and total acidity in therapeutic groups compared to vehicle control and thereby significantly (P<0.01) increased percentage inhibition of ulcers and protected area which was evident by the significant rise in pH of gastric content. The effect of extracts was dose-dependent and results were comparable to that of standard drug omeprazole. Conclusion: The results obtained from the present work suggest that the methanol extract of Tephrosia villosa possess significant anti-ulcer potentials against experimentally induced ulcers in albino rats. |
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
9 (RLIN) | 4774 |
Topical term or geographic name entry element | PHARMACOLOGY |
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9 (RLIN) | 15493 |
Co-Author | Ramesh C. |
700 ## - ADDED ENTRY--PERSONAL NAME | |
9 (RLIN) | 15048 |
Co-Author | PRAMANIK, S. |
773 0# - HOST ITEM ENTRY | |
Place, publisher, and date of publication | Bhopal Innovare Academic Sciences Pvt Ltd |
Title | International journal of pharmacy and pharmaceutical science |
International Standard Serial Number | 2656-0097 |
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URL | https://innovareacademics.in/journals/index.php/ijpps/article/view/41277/25552 |
Link text | Full Article |
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Source of classification or shelving scheme | |
Koha item type | Articles Abstract Database |
Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Collection code | Permanent Location | Current Location | Shelving location | Date acquired | Barcode | Date last seen | Price effective from | Koha item type |
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Circulation | School of Pharmacy | School of Pharmacy | Archieval Section | 2022-01-19 | 2022-0125 | 2022-01-19 | 2022-01-19 | Articles Abstract Database |