000 -LEADER |
fixed length control field |
a |
003 - CONTROL NUMBER IDENTIFIER |
control field |
OSt |
005 - DATE AND TIME OF LATEST TRANSACTION |
control field |
20220208093807.0 |
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
fixed length control field |
220208b xxu||||| |||| 00| 0 eng d |
040 ## - CATALOGING SOURCE |
Original cataloging agency |
AIKTC-KRRC |
Transcribing agency |
AIKTC-KRRC |
100 ## - MAIN ENTRY--PERSONAL NAME |
9 (RLIN) |
15892 |
Author |
Dighe, Amol Sopanrao |
245 ## - TITLE STATEMENT |
Title |
In silico investigation and molecular docking study of triazolo-thiadiazole derivatives for antimicrobial, anti-inflammatory and anti-diabetic activity |
250 ## - EDITION STATEMENT |
Volume, Issue number |
Vol.55(4), Oct-Dec |
260 ## - PUBLICATION, DISTRIBUTION, ETC. |
Place of publication, distribution, etc. |
Karnataka |
Name of publisher, distributor, etc. |
Association of Pharmaceutical Teachers of India (APTI) |
Year |
2021 |
300 ## - PHYSICAL DESCRIPTION |
Pagination |
1125-1144p. |
520 ## - SUMMARY, ETC. |
Summary, etc. |
Triazolo-thiadiazole and connected fused ring in heterocyclic compounds are of highly interest in potential bioactive molecules. Triazolo-thiadiazole derivatives have lead of organic chemists due to their good biological and chemotherapeutic significance. Research in the field of anti-mycobacterium, anti-inflammatory, anti-diabetic and anti- microbial therapies are ongoing and studies are seeking. Therefore, the discovery of new effective anti-mycobacterium, anti-inflammatory, anti-diabetic and antimicrobial agents are imperative. Swiss programs are used to predict Triazolo-thiadiazole derivatives properties that are important for drug profile. Later, all of them were docked into the active sites of enzymes namely Ribosomal RNA large subunit methyltransferase (1P91), PeriplasmicOligopeptide-Binding Protein (1B05) and Protein-tyrosine phosphatase, non-receptor type 1 (1q6s), those were considered in Antidiabetic studies of triazolo- thiazazole derivative. Docking study when compared with Triazolo-thiadiazole derivatives with standard drug, derivative docking result is better. Ciprofloxacin, ibuprofen, and acarbose have been used as standard drugs for antimicrobial, anti-inflammatory and anti- diabetic activity in comparative docking studies. |
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
9 (RLIN) |
4639 |
Topical term or geographic name entry element |
PHARMACEUTICS |
700 ## - ADDED ENTRY--PERSONAL NAME |
9 (RLIN) |
15893 |
Co-Author |
Sen, Ashim Kumar |
773 0# - HOST ITEM ENTRY |
Place, publisher, and date of publication |
Bengluru Association of Pharmaceutical Teachers of India (APTI) |
International Standard Serial Number |
0019-5464 |
Title |
Indian journal of pharmaceutical education and research |
856 ## - ELECTRONIC LOCATION AND ACCESS |
URL |
https://www.ijper.org/sites/default/files/IndJPhaEdRes-55-4-1125.pdf |
Link text |
Click here |
942 ## - ADDED ENTRY ELEMENTS (KOHA) |
Source of classification or shelving scheme |
|
Koha item type |
Articles Abstract Database |