Antimicrobial agent’s utilization and cost pattern in medical intensive care unit of a tertiary care hospital (Record no. 16275)
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fixed length control field | a |
003 - CONTROL NUMBER IDENTIFIER | |
control field | OSt |
005 - DATE AND TIME OF LATEST TRANSACTION | |
control field | 20220208145426.0 |
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
fixed length control field | 220208b xxu||||| |||| 00| 0 eng d |
040 ## - CATALOGING SOURCE | |
Original cataloging agency | AIKTC-KRRC |
Transcribing agency | AIKTC-KRRC |
100 ## - MAIN ENTRY--PERSONAL NAME | |
9 (RLIN) | 15948 |
Author | Sartaj Hussain |
245 ## - TITLE STATEMENT | |
Title | Antimicrobial agent’s utilization and cost pattern in medical intensive care unit of a tertiary care hospital |
250 ## - EDITION STATEMENT | |
Volume, Issue number | Vol.13(2) |
260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
Place of publication, distribution, etc. | M P |
Name of publisher, distributor, etc. | Innovare Academic Sciences Pvt Ltd |
Year | 2021 |
300 ## - PHYSICAL DESCRIPTION | |
Pagination | 89-93p. |
520 ## - SUMMARY, ETC. | |
Summary, etc. | Objective: The objective of this study was to evaluate the utilization and cost pattern of AMAs (Antimicrobial Agents) in the Medical ICU of a tertiary care teaching hospital, and to determine the predictor of antimicrobial number per day. Methods: A prospective cross-sectional study was carried out and a total of 101 patients were studied. The drugs were classified into different groups according to the World Health Organization’s ATC (Anatomical Therapeutic Chemical) Classification System. Results: The mean [95% confidence interval (CI)] duration of ICU stay was 7.11 (5.70-8.52) days and the mortality rate in the ICU was 42.6%. The AMAs DDD (Defined Daily Dose) per 100 patient days and number of AMAs per prescription were 296.64 and 2.65, respectively. Piperacillin-tazobactam was the most commonly utilized AMAs followed by metronidazole, meropenem, fluconazole, and colistin. The mean number [95% CI] of AMAs, DDD, and cost (INR) per patient were 18.82 (14.05-23.59), 21.09 (15.36-26.81) and 25,827 (18,716-32,939) respectively. The AMAs constituted 88.53% of the total treatment cost. Meropenem was the most costly AMA (32.10% of the total AMAs cost) followed by imipenem-cilastatin (20.50%), colistin (14.65%), piperacillin-tazobactam (8.40%), and clindamycin (4.47%). The independent predictor for the antimicrobial number per day was acute physiology and chronic health evaluation II (APACHE-II) score at admission and nosocomial infections. Conclusion: The AMAs, DDD per 100 patient days, and number per prescription were higher. This leads to a higher cost of AMAs per patient and the AMAs cost out of the total cost as compared to previous studies. We suggest, there is a need to formulate and implement an antimicrobial restriction policy. |
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
9 (RLIN) | 4639 |
Topical term or geographic name entry element | PHARMACEUTICS |
700 ## - ADDED ENTRY--PERSONAL NAME | |
9 (RLIN) | 15949 |
Co-Author | Yadav, Suraj Singh |
773 0# - HOST ITEM ENTRY | |
Title | International journal of pharmacy and pharmaceutical science |
International Standard Serial Number | 2656-0097 |
Place, publisher, and date of publication | Bhopal Innovare Academic Sciences Pvt Ltd |
856 ## - ELECTRONIC LOCATION AND ACCESS | |
URL | https://innovareacademics.in/journals/index.php/ijpps/article/view/41338 |
Link text | Click here |
942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
Source of classification or shelving scheme | |
Koha item type | Articles Abstract Database |
Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Permanent Location | Current Location | Shelving location | Date acquired | Barcode | Date last seen | Price effective from | Koha item type |
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School of Pharmacy | School of Pharmacy | Archieval Section | 2022-02-08 | 2022-0418 | 2022-02-08 | 2022-02-08 | Articles Abstract Database |