000 -LEADER |
fixed length control field |
a |
003 - CONTROL NUMBER IDENTIFIER |
control field |
OSt |
005 - DATE AND TIME OF LATEST TRANSACTION |
control field |
20220211095050.0 |
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
fixed length control field |
220211b xxu||||| |||| 00| 0 eng d |
040 ## - CATALOGING SOURCE |
Original cataloging agency |
AIKTC-KRRC |
Transcribing agency |
AIKTC-KRRC |
100 ## - MAIN ENTRY--PERSONAL NAME |
9 (RLIN) |
16054 |
Author |
Mathew, CICI |
245 ## - TITLE STATEMENT |
Title |
Design, synthesis and antimicrobial studies of 5-benzylidene substituted rhodanine containing heterocycles |
250 ## - EDITION STATEMENT |
Volume, Issue number |
Vol.13(5) |
260 ## - PUBLICATION, DISTRIBUTION, ETC. |
Place of publication, distribution, etc. |
M P |
Name of publisher, distributor, etc. |
Innovare Academic Sciences Pvt Ltd |
Year |
2021 |
300 ## - PHYSICAL DESCRIPTION |
Pagination |
28-34p. |
520 ## - SUMMARY, ETC. |
Summary, etc. |
Objective: The principal objective of the study was to synthesize and evaluate the biological activities of a novel class of 5-benzylidene substituted rhodanine derivatives as antimicrobial agents.Methods: All the synthesized compounds (D1-D10) were screened for their antimicrobial activities using microdilution methods as per the reported procedure.All compounds were evaluated as potential antimicrobial agents against gram-positive bacteria: Bacillus cereus, Staphylococcus aureus, gram negative bacteria: Escherichia coli Pseudomonas aeruginosa and Klebsiella pneumoniae Fungal cultures used in the study were Aspergillus niger, Candida albicans, Candida parapsilosis, Candida tropicalis and Candida glabrata.Results: Compound D6 showed good antifungal activity in the MIC range 16μg/mlagainst Candida tropicalisand Compound D10 showed good antifungal activity in the MIC range 16μg/mlagainst Candida glabrata. Compounds D2 and D5 showed good antibacterial activity at 32μg/ml. all the other compounds showed moderate antibacterial activity. Conclusion: Based on the above results, it can be concluded that the compounds may leadto the development of more potent antimicrobial drug candidates in the near future. |
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
9 (RLIN) |
4639 |
Topical term or geographic name entry element |
PHARMACEUTICS |
700 ## - ADDED ENTRY--PERSONAL NAME |
9 (RLIN) |
16056 |
Co-Author |
Saraswati, Bindu |
773 0# - HOST ITEM ENTRY |
Place, publisher, and date of publication |
Bhopal Innovare Academic Sciences Pvt Ltd |
International Standard Serial Number |
2656-0097 |
Title |
International journal of pharmacy and pharmaceutical science |
856 ## - ELECTRONIC LOCATION AND ACCESS |
URL |
https://innovareacademics.in/journals/index.php/ijpps/article/view/40106/24708 |
Link text |
Click here |
942 ## - ADDED ENTRY ELEMENTS (KOHA) |
Source of classification or shelving scheme |
|
Koha item type |
Articles Abstract Database |