Correlation of serum albumin and creatinine with oxidative stress markers in patients having nephrotic syndrome (Record no. 16962)

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005 - DATE AND TIME OF LATEST TRANSACTION
control field 20220629115122.0
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fixed length control field 220629b xxu||||| |||| 00| 0 eng d
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Original cataloging agency AIKTC-KRRC
Transcribing agency AIKTC-KRRC
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9 (RLIN) 16896
Author Parmar, Glory S.
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Title Correlation of serum albumin and creatinine with oxidative stress markers in patients having nephrotic syndrome
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Volume, Issue number Vol.13(12)
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Place of publication, distribution, etc. M P
Name of publisher, distributor, etc. Innovare Academic Sciences Pvt Ltd
Year 2021
300 ## - PHYSICAL DESCRIPTION
Pagination 20-24p.
520 ## - SUMMARY, ETC.
Summary, etc. Objective: Children with nephrotic syndrome (NS) have a stressful condition, and oxidative damage may impair their treatment response. This study aims to gain a better understanding of the relationship between oxidative stress and NS to lay the basis for further research into improved diagnostic options, treatment, and prevention of the disease. Methods: We took a blood sample from 100 Indian patients aged 2-14 y. Each patient was tested for oxidative stress. The buege method was used to assess MDA levels in patients. The pyrogallol method was used to measure SOD activity in blood serum, and the jollow method was used to measure glutathione levels.Results: The levels of oxidative stress markers (MDA, SOD, and GSH) were compared between NS patients and the control. SOD and GSHconcentrations were significantly decreased in the NS group when compared to the control. In contrast, MDA level was significantly higher in the NSgroup than in the control. In the correlation analysis, we found that the serum SOD activity was significantly positively correlated with serumalbumin and creatinine level in patients with NS. Thus, oxidative stress in children with NS is indicated by reduced antioxidant potential because of low albumin. Therefore, it is thought that oxidative stress is implicated in the development of NS in Indian children. Conclusion: We concluded that oxidative stress was intensified in children with NS due to decreased antioxidant levels caused by hypoalbuminemia.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
9 (RLIN) 4639
Topical term or geographic name entry element PHARMACEUTICS
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9 (RLIN) 7153
Co-Author Mistry, Kinnari N.
773 0# - HOST ITEM ENTRY
International Standard Serial Number 2656-0097
Title International journal of pharmacy and pharmaceutical science
Place, publisher, and date of publication Bhopal Innovare Academic Sciences Pvt Ltd
856 ## - ELECTRONIC LOCATION AND ACCESS
URL https://innovareacademics.in/journals/index.php/ijpps/article/view/42931/25740
Link text Click here
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme
Koha item type Articles Abstract Database
Holdings
Withdrawn status Lost status Source of classification or shelving scheme Damaged status Not for loan Permanent Location Current Location Shelving location Date acquired Barcode Date last seen Price effective from Koha item type
          School of Pharmacy School of Pharmacy Archieval Section 2022-06-29 2022-0955 2022-06-29 2022-06-29 Articles Abstract Database
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