Phytochemical investigation, liquid chromatography-mass spectrometry analysis, antibacterial and anthelminthic activity of lindernia crustacea (l.) f. Muell. (Record no. 17255)

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control field 20220730163927.0
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040 ## - CATALOGING SOURCE
Original cataloging agency AIKTC-KRRC
Transcribing agency AIKTC-KRRC
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9 (RLIN) 17460
Author Ghori, S. S.
245 ## - TITLE STATEMENT
Title Phytochemical investigation, liquid chromatography-mass spectrometry analysis, antibacterial and anthelminthic activity of lindernia crustacea (l.) f. Muell.
250 ## - EDITION STATEMENT
Volume, Issue number Vol.83(6), Nov-Dec
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Place of publication, distribution, etc. Mumbai
Name of publisher, distributor, etc. Indian Journal of Pharmaceutical Science
Year 2021
300 ## - PHYSICAL DESCRIPTION
Pagination 1314-1319p.
520 ## - SUMMARY, ETC.
Summary, etc. Lindernia crustacea (L.) F. Muell is one of the commonly used medicinal plants native to India, Indonesia and Malaysia. In the present investigation antibacterial activity of leaf and stem petroleum ether and methanolic extracts was performed at 25 μg/ml, 50 μg/ml, 75 μg/ml and 100 μg/ml concentrations and anthelminthic activity of leaf methanolic extract was performed at 25 μg/ml, 75 μg/ml and 100 μg/ml concentrations. The powdered leaf and stem were extracted by soxhlation and the phytochemical screening of the extracts was performed for detection of phytoconstituents. The leaf petroleum ether and methanolic extracts showed the presence of alkaloids, carbohydrates, tannins and glycosides, whereas the stem petroleum ether and methanolic extracts showed alkaloids, carbohydrates, flavonoids and tannins. Antibacterial activity was performed by cup and plate method using Staphylococcus aureus and Escherichia coli with Penicillin G as standard. Antibacterial activity was not found in both stem and leaf extracts. Anthelminthic activity was performed using Indian earthworm, with albendazole as standard drug. The leaf methanolic extract showed significant anthelminthic activity at 100 μg/ml with paralysis time of 58±3.978 and death time of 79±4.796 as compared with standard drug. The anthelminthic activity of methanolic extract might be due the presence of phytoconstituents as identified by liquid chromatography-mass spectrometry analysis.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
9 (RLIN) 4639
Topical term or geographic name entry element PHARMACEUTICS
700 ## - ADDED ENTRY--PERSONAL NAME
9 (RLIN) 17461
Co-Author Fouzia Tehseen
773 0# - HOST ITEM ENTRY
Title Indian journal of pharmaceutical sciences
Place, publisher, and date of publication New Delhi
856 ## - ELECTRONIC LOCATION AND ACCESS
URL https://www.ijpsonline.com/articles/phytochemical-investigation-liquid-chromatographymass-spectrometry-analysis-antibacterial-and-anthelminthic-activity-of-emlinderni-4401.html
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          School of Pharmacy School of Pharmacy Archieval Section 2022-07-30 2022-1257 2022-07-30 2022-07-30 Articles Abstract Database
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