Evaluation of the effect of methotrexate on psoriasis based on specialized pharmaceutical education (Record no. 17353)
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| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | OSt |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20220829102446.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 220829b xxu||||| |||| 00| 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | AIKTC-KRRC |
| Transcribing agency | AIKTC-KRRC |
| 100 ## - MAIN ENTRY--PERSONAL NAME | |
| 9 (RLIN) | 17643 |
| Author | Wang, Lan |
| 245 ## - TITLE STATEMENT | |
| Title | Evaluation of the effect of methotrexate on psoriasis based on specialized pharmaceutical education |
| 250 ## - EDITION STATEMENT | |
| Volume, Issue number | Vol.56(2), Apr-June |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Karnataka |
| Name of publisher, distributor, etc. | Association of Pharmaceutical Teachers of India (APTI) |
| Year | 2022 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Pagination | 364-371p. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Background: Methotrexate (MTX) is still the gold standard therapy for moderate to severe psoriasis. There is a marked interpersonal variation in the therapeutic response and toxicity profile of MTX which brings difficulty for clinical application. Objectives: To establish the specialized pharmaceutical education (SPE) mode for psoriasis administrated with MTX and assess the therapeutic effect between cases received SPE and usual health care in the real-world. Materials and Methods: In this retrospective cohort study, patients of usual health care received prescription as proof of properly taking medicine and being required return to the hospital every 4 weeks. Patients of SPE intervention were referred to the pharmaceutical clinic every 4 weeks. Body surface area(BSA), psoriasis area severity index (PASI) of 0, 4, 8, 12 week, PASI 75 of 12 week and times of self- adjusting dosage were observational noted and analyzed. Results: Records of 12 cases of usual care and 16 cases of SPE received MTX for psoriasis were reviewed. The decline range of BSA of SPE was higher than that of usual care at 4 week, and the difference was statistically significant ( p=0.043).The decline range of PASI of SPE was higher than that of usual care at 8 week and 12 week with statistically significant difference separately ( p=0.048; p=0.029).Times of self-adjusting dosage was zero of SPE and was statistically significant different compared to that of usual care ( p=0.026). Conclusion: Statistical significant faster improvement on efficacy with no significant difference of safety in the SPE than usual care came to the conclusion. The SPE conducted by the pharmacists appears suitable for the real world implementation. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| 9 (RLIN) | 4639 |
| Topical term or geographic name entry element | PHARMACEUTICS |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| 9 (RLIN) | 17644 |
| Co-Author | Shu, Dan |
| 773 0# - HOST ITEM ENTRY | |
| Place, publisher, and date of publication | Bengluru Association of Pharmaceutical Teachers of India (APTI) |
| International Standard Serial Number | 0019-5464 |
| Title | Indian journal of pharmaceutical education and research |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| URL | https://www.ijper.org/sites/default/files/IndJPhaEdRes-56-2-364_0.pdf |
| Link text | Click here |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | |
| Koha item type | Articles Abstract Database |
| Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Permanent Location | Current Location | Shelving location | Date acquired | Barcode | Date last seen | Price effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| School of Pharmacy | School of Pharmacy | Archieval Section | 2022-08-29 | 2022-1420 | 2022-08-29 | 2022-08-29 | Articles Abstract Database |