Chemometric assisted spectrophotometric method development for evaluation of torsemide and eplerenone in their combined tablet dosage forms (Record no. 17634)
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| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | OSt |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20220923151924.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 220923b xxu||||| |||| 00| 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | AIKTC-KRRC |
| Transcribing agency | AIKTC-KRRC |
| 100 ## - MAIN ENTRY--PERSONAL NAME | |
| 9 (RLIN) | 18084 |
| Author | Madhuri A. |
| 245 ## - TITLE STATEMENT | |
| Title | Chemometric assisted spectrophotometric method development for evaluation of torsemide and eplerenone in their combined tablet dosage forms |
| 250 ## - EDITION STATEMENT | |
| Volume, Issue number | Vol.56(1), Jan-Mar |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Karnataka |
| Name of publisher, distributor, etc. | Association of Pharmaceutical Teachers of India (APTI) |
| Year | 2022 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Pagination | 253-263p. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Aim: In a present work two drugs Torsemide and Eplerenone were estimated from their combined tablet dosage forms by applying chemometric assisted spectrophotometric method. Methods: The methods are based on chemometrics a (multivariate) method which includes classical least square (CLS) and inverse least square (ILS). These methods were employed for simultaneous determination of Torsemide and Eplerenone in tablet dosage forms without any prior separation of components. For these methods the overlapping spectra of two drugs not subjected any conversions. The data processing of chemometric was accomplished by using software named Chemometrics Toolbox 3.02 which is associated with MATLAB 6 and excel. Results: The results obtained from CLS and ILS methods were compared statistically. These chemometric methods were applied for the determination of these two drugs in their marketed tablet dosage form without any prior separation procedure of the drugs. The mean percent recoveries and values of relative standard deviation for these two methods were found to be 99.72/0.536 for Torsemide and 100.06/0.384 for Eplerenone. Conclusion: The two chemometric methods developed can be successfully applied for the quantitative estimation of drugs from their dosage form. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| 9 (RLIN) | 4639 |
| Topical term or geographic name entry element | PHARMACEUTICS |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| 9 (RLIN) | 18086 |
| Co-Author | Patel, Dipti |
| 773 0# - HOST ITEM ENTRY | |
| Place, publisher, and date of publication | Bengluru Association of Pharmaceutical Teachers of India (APTI) |
| Title | Indian journal of pharmaceutical education and research |
| International Standard Serial Number | 0019-5464 |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| URL | https://www.ijper.org/sites/default/files/IndJPhaEdRes-56-1-255.pdf |
| Link text | Click here |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | |
| Koha item type | Articles Abstract Database |
| Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Permanent Location | Current Location | Shelving location | Date acquired | Barcode | Date last seen | Price effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| School of Pharmacy | School of Pharmacy | Archieval Section | 2022-09-23 | 2022-1724 | 2022-09-23 | 2022-09-23 | Articles Abstract Database |