Mechanism of long non-coding RNA MAGI2- antisense RNA 3 targeting microRNA-31-5p to regulate proliferation and metastasis of SiHa cells in cervical cancer (Record no. 18330)
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fixed length control field | a |
003 - CONTROL NUMBER IDENTIFIER | |
control field | OSt |
005 - DATE AND TIME OF LATEST TRANSACTION | |
control field | 20221122143151.0 |
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
fixed length control field | 221122b xxu||||| |||| 00| 0 eng d |
040 ## - CATALOGING SOURCE | |
Original cataloging agency | AIKTC-KRRC |
Transcribing agency | AIKTC-KRRC |
100 ## - MAIN ENTRY--PERSONAL NAME | |
9 (RLIN) | 19226 |
Author | Yang, Jingyan |
245 ## - TITLE STATEMENT | |
Title | Mechanism of long non-coding RNA MAGI2- antisense RNA 3 targeting microRNA-31-5p to regulate proliferation and metastasis of SiHa cells in cervical cancer |
250 ## - EDITION STATEMENT | |
Volume, Issue number | Vol.84(2), Mar-Apr |
260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
Place of publication, distribution, etc. | Mumbai |
Name of publisher, distributor, etc. | Indian Journal of Pharmaceutical Science |
Year | 2022 |
300 ## - PHYSICAL DESCRIPTION | |
Pagination | 477-482p. |
520 ## - SUMMARY, ETC. | |
Summary, etc. | To investigate the effect of long non coding RNA MAGI2-antisense RNA 3 on the proliferation, invasion and migration of cervical cancer cells and the underlying mechanism. SiHa cells were divided into plasmid cloning DNA group, plasmid cloning DNA-MAGI2-antisense RNA 3 group, anti-microRNA-negative control group, anti-microRNA-31-5p group, plasmid cloning DNA-MAGI2-antisense RNA 3+microRNA- negative control group and plasmid cloning DNA-MAGI2-antisense RNA 3+microRNA-31-5p group; quantitative reverse transcription polymerase chain reaction was used to determine the messenger RNA expression levels of microRNA-31-5p and MAGI2-antisense RNA 3; cell viability was detected by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-2H-tetrazolium bromide assay; the number of cell migration and invasion in each group was detected by Transwell assay; dual luciferase reporter assay was performed to detect the fluorescence activity. The expression levels of microRNA-31-5p were significantly increased and those of MAGI2-antisense RNA 3 messenger RNA were decreased in cervical cancer cell lines (p<0.05); overexpression of MAGI2-antisense RNA 3 or inhibition expression of microRNA-31-5p could suppress SiHa cell proliferation, migration and invasion (p<0.05). MAGI2-antisense RNA 3 targeted regulation of microRNA-31-5p; overexpression of microRNA-31-5p partially reversed the inhibitory effects of overexpressing MAGI2-antisense RNA 3 on the proliferation, migration, invasion of SiHa cells. Long non coding RNA MAGI2-antisense RNA 3 can inhibit cervical cancer cell proliferation, migration and invasion by regulating microRNA-31-5p. |
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
9 (RLIN) | 4639 |
Topical term or geographic name entry element | PHARMACEUTICS |
700 ## - ADDED ENTRY--PERSONAL NAME | |
9 (RLIN) | 19227 |
Co-Author | Chen, Jing |
773 0# - HOST ITEM ENTRY | |
Place, publisher, and date of publication | New Delhi |
Title | Indian journal of pharmaceutical sciences |
856 ## - ELECTRONIC LOCATION AND ACCESS | |
URL | https://www.ijpsonline.com/articles/mechanism-of-long-noncoding-rna-magi2antisense-rna-3-targeting-microrna315p-to-regulate-proliferation-and-metastasis-of-.pdf |
Link text | Click here |
942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
Source of classification or shelving scheme | |
Koha item type | Articles Abstract Database |
Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Permanent Location | Current Location | Shelving location | Date acquired | Barcode | Date last seen | Price effective from | Koha item type |
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School of Pharmacy | School of Pharmacy | Archieval Section | 2022-11-22 | 2022-2189 | 2022-11-22 | 2022-11-22 | Articles Abstract Database |