Recent advances in curcumin: An integrative overview of its mode of action, pharmacological properties, and health benefits (Record no. 18421)

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040 ## - CATALOGING SOURCE
Original cataloging agency AIKTC-KRRC
Transcribing agency AIKTC-KRRC
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9 (RLIN) 18813
Author Arvind Kumar
245 ## - TITLE STATEMENT
Title Recent advances in curcumin: An integrative overview of its mode of action, pharmacological properties, and health benefits
250 ## - EDITION STATEMENT
Volume, Issue number Vol.16(3), Jul-Sep
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Place of publication, distribution, etc. Mandsaur
Name of publisher, distributor, etc. BRNSS Publication Hub.
Year 2022
300 ## - PHYSICAL DESCRIPTION
Pagination 226-235p.
520 ## - SUMMARY, ETC.
Summary, etc. Turmeric (Curcuma longa) is used as a spice, preservative, and coloring matter and has a wide range of medicinal
and pharmacological applications. Curcumin, a polyphenolic herbal product, well-known shows healing hobby
for some of the diseases, attributed specially to its chemical shape and specific physical, chemical, and organic
properties. The oxidative damage and inflammation have been pointed out as the root cause of many chronic
diseases such as cancer, diabetes, hypertension, and Alzheimer’s disease. Curcumin and its analogs prevent
oxidative damage and inhibit the binding of toxic metabolites to DNA. The safety studies indicate that turmeric is
well tolerated at a very high dose (0.5–1.5 g/day/person) without any toxic effects. Epidemiological and clinical
studies of curcumin suggested that cancer could be prevented or significantly reduced by treatment with anti-
oxidant and anti-inflammatory drugs, therefore, Curcumin, an anti-oxidant and anti-inflammatory compound
found in turmeric (a curry spice), could be a promising option for the prevention and/or treatment of cancer
and other chronic diseases. Curcumin, a highly pleiotropic drug with a great safety profile and strong molecular
evidence targeting various diseases, could not attain its optimal therapeutic effect in previous clinical studies,
owing to its limited solubility and poor absorption. Curcumin can be developed as a medicinal medication by
enhancing its absorption and cellular uptake through better formulation qualities or delivery mechanisms. This
review focuses on the properties, chemistry, toxicity studies, dosage, and the possibilities of the therapeutic
application of curcumin for the prevention and/or treatment of several diseases, and their safety profile.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
9 (RLIN) 4639
Topical term or geographic name entry element PHARMACEUTICS
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9 (RLIN) 19346
Co-Author Chandel, Saket Singh
773 0# - HOST ITEM ENTRY
Place, publisher, and date of publication Mandsaur B.R. Nahata Smriti Sansthan
International Standard Serial Number 0973-8258
Title International journal of green pharmacy
856 ## - ELECTRONIC LOCATION AND ACCESS
URL https://www.greenpharmacy.info/index.php/ijgp/article/view/3298/1239
Link text Click here
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme
Koha item type Articles Abstract Database
Holdings
Withdrawn status Lost status Source of classification or shelving scheme Damaged status Not for loan Permanent Location Current Location Shelving location Date acquired Barcode Date last seen Price effective from Koha item type
          School of Pharmacy School of Pharmacy Archieval Section 2022-12-06 2022-2292 2022-12-06 2022-12-06 Articles Abstract Database
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