To evaluate the safety and efficacy of amlodipine and chlorthalidone in combination with telmisartan in hypertensive patients attending tertiary care centre, Telangana (Record no. 18799)

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control field 20230204145039.0
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fixed length control field 230204b xxu||||| |||| 00| 0 eng d
040 ## - CATALOGING SOURCE
Original cataloging agency AIKTC-KRRC
Transcribing agency AIKTC-KRRC
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9 (RLIN) 19883
Author Valishetti, Manoj Kumar
245 ## - TITLE STATEMENT
Title To evaluate the safety and efficacy of amlodipine and chlorthalidone in combination with telmisartan in hypertensive patients attending tertiary care centre, Telangana
250 ## - EDITION STATEMENT
Volume, Issue number Vol.14(11)
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Place of publication, distribution, etc. M P
Name of publisher, distributor, etc. Innovare Academic Sciences Pvt Ltd
Year 2022
300 ## - PHYSICAL DESCRIPTION
Pagination 37-42p.
520 ## - SUMMARY, ETC.
Summary, etc. Objective:The main objective of this study is to evaluate and compare the effects of both treatments on systolic and diastolic blood pressure in 4th, and 8th weeks with baselineMethods:A prospective, comparative, Open-label, and parallel-group clinical study was conducted in out patient's department of general medicine at Osmania general hospital. 120 patients were randomly allocated into 2 groups. Group 1 with 60 patients received Tab: Telmisartan 40 mg+Amlodipine 5 mg once daily, and Group 2 with 60 patients received Tab: Telmisartan 40 mg+ Chlorthalidone 6.25 mg once daily for a period of 8 w. Follow-up was done in the 4th week and 8th week to evaluate the safety and efficacy in hypertensive patients.Results: The differences in the SBP, DBP, and HR in group A (P value<0.001) and group B (P value<0.001) at the 4th week and 8th week follow-up periods with baseline value (0 w) were statistically significant as P value<0.05.Conclusion: The combination of telmisartan plus amlodipine is equally effective as the combination of telmisartan plus chlorthalidone in decreasing SBP, DBP, HR, and MAP. No major adverse drug reactions were noted during the study period.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
9 (RLIN) 4639
Topical term or geographic name entry element PHARMACEUTICS
700 ## - ADDED ENTRY--PERSONAL NAME
9 (RLIN) 19884
Co-Author Yasarapu, Madhu
773 0# - HOST ITEM ENTRY
International Standard Serial Number 2656-0097
Place, publisher, and date of publication Bhopal Innovare Academic Sciences Pvt Ltd
Title International journal of pharmacy and pharmaceutical science
856 ## - ELECTRONIC LOCATION AND ACCESS
URL https://innovareacademics.in/journals/index.php/ijpps/article/view/46070/27138
Link text Click here
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme
Koha item type Articles Abstract Database
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          School of Pharmacy School of Pharmacy Archieval Section 2023-02-04 2023-0252 2023-02-04 2023-02-04 Articles Abstract Database
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