| 000 -LEADER |
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| fixed length control field |
a |
| 003 - CONTROL NUMBER IDENTIFIER |
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| control field |
OSt |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
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| control field |
20230206101143.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
230206b xxu||||| |||| 00| 0 eng d |
| 040 ## - CATALOGING SOURCE |
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| Original cataloging agency |
AIKTC-KRRC |
| Transcribing agency |
AIKTC-KRRC |
| 100 ## - MAIN ENTRY--PERSONAL NAME |
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| 9 (RLIN) |
19897 |
| Author |
Pooja Gurav |
| 245 ## - TITLE STATEMENT |
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| Title |
Bioanalytical method for estimation of teriflunomide in human plasma |
| 250 ## - EDITION STATEMENT |
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| Volume, Issue number |
Vol.14(9) |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
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| Place of publication, distribution, etc. |
M P |
| Name of publisher, distributor, etc. |
Innovare Academic Sciences Pvt Ltd |
| Year |
2022 |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Pagination |
19-23p. |
| 520 ## - SUMMARY, ETC. |
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| Summary, etc. |
Objective: Teriflunomide is used for the treatment of multiple sclerosis and is available in 7 mg and 14 mg tablets. This study aimed to develop and validate a simple and economical HPTLC method for the estimation of Teriflunomide in human plasma.Methods: HPTLC method was developed using toluene: ethyl acetate: acetic acid as the mobile phase and the stationary phase was a TLC plate precoated with silica gel 60 F254. The detection wavelength set was 294 nm. The sample preparation involved a simple protein precipitation technique with Acetonitrile as a precipitating protein agent; the internal standard selected was Rilpivirine. The validation was carried out as per bio-analytical method guidelines.Results: The Rf value for Teriflunomide was found to be 0.46±0.04. The linearity range was observed from 10-60 μg/ml with a regression coefficient value of 0.9819. The developed method was validated for various parameters like specificity, linearity, accuracy, precision, recovery, and stability.Conclusion: The developed method is simple, specific, accurate, and economical for the estimation of Teriflunomide in human plasma. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| 9 (RLIN) |
4639 |
| Topical term or geographic name entry element |
PHARMACEUTICS |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| 9 (RLIN) |
19898 |
| Co-Author |
Damle, Mrinalini |
| 773 0# - HOST ITEM ENTRY |
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| Title |
International journal of pharmacy and pharmaceutical science |
| International Standard Serial Number |
2656-0097 |
| Place, publisher, and date of publication |
Bhopal Innovare Academic Sciences Pvt Ltd |
| 856 ## - ELECTRONIC LOCATION AND ACCESS |
|---|
| URL |
https://innovareacademics.in/journals/index.php/ijpps/article/view/45151/26866 |
| Link text |
Click here |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
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| Source of classification or shelving scheme |
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| Koha item type |
Articles Abstract Database |
