Synthesis of some ethoxyphthalimide derivatives of pyrazoloisoxazoles and pyrazolopyrimidines and their antimicrobial and anticancer screening (Record no. 19271)

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005 - DATE AND TIME OF LATEST TRANSACTION
control field 20230502122013.0
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 230502b xxu||||| |||| 00| 0 eng d
040 ## - CATALOGING SOURCE
Original cataloging agency AIKTC-KRRC
Transcribing agency AIKTC-KRRC
100 ## - MAIN ENTRY--PERSONAL NAME
9 (RLIN) 20625
Author Joshi, Swati
245 ## - TITLE STATEMENT
Title Synthesis of some ethoxyphthalimide derivatives of pyrazoloisoxazoles and pyrazolopyrimidines and their antimicrobial and anticancer screening
250 ## - EDITION STATEMENT
Volume, Issue number Vol.61(7), Jul
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Place of publication, distribution, etc. New Delhi
Name of publisher, distributor, etc. CSIR
Year 2022
300 ## - PHYSICAL DESCRIPTION
Pagination 723-731p.
520 ## - SUMMARY, ETC.
Summary, etc. Synthesis of 4-arylidene-5-methyl-2,4-dihydro-3H-pyrazol-3-one (IIIa-d) has been achieved by the condensation reaction between 5-methyl-2,4-dihydro-3H-pyrazol-3-one (I) and 4-substituted benzaldehydes (IIa-d). Ethyl acetoacetate and hydrazine hydrate in absolute alcohol undergo cyclization reaction to give (I). 4-Arylidene-5-methyl-2,4-dihydro-3H-pyrazol-3-ones (IIIa-d) have been converted to corresponding ethoxyphthalimide derivatives (IVa-d) by treatment with phthalimidoxyethyl bromide (A). 1-N-Ethoxyphthalimido-3-methyl-4-(4-substituted benzylidene) pyrazol-5-one (IVa-d) has been reacted with hydroxylamine hydrochloride and guanidine nitrate separately to yield ethoxyphthalimide substituted pyrazolo[3,4-c]isoxazoles (Va-d) and pyrazolo[3,4-d]pyrimidines (VIa-d) respectively. All the compounds have been characterized by elemental and spectral analysis mainly IR, 1H NMR and mass spectroscopy. Synthesized compounds have also been screened for various biological activities viz. antibacterial, antifungal, antiviral and anticancer.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
9 (RLIN) 5009
Topical term or geographic name entry element GENERAL CHEMISTRY
700 ## - ADDED ENTRY--PERSONAL NAME
9 (RLIN) 20626
Co-Author Talesara, G. L.
773 0# - HOST ITEM ENTRY
Place, publisher, and date of publication New Delhi NISCAIR-CSIR 2005
International Standard Serial Number 0019-5103
Title Indian journal of chemistry (Section B)
856 ## - ELECTRONIC LOCATION AND ACCESS
URL http://op.niscpr.res.in/index.php/IJC/article/view/64633
Link text Click here
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme
Koha item type Articles Abstract Database
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Withdrawn status Lost status Source of classification or shelving scheme Damaged status Not for loan Permanent Location Current Location Shelving location Date acquired Barcode Date last seen Price effective from Koha item type
          School of Pharmacy School of Pharmacy Archieval Section 2023-05-02 2023-0778 2023-05-02 2023-05-02 Articles Abstract Database
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