Design of an efficient three component one-pot synthesis of -1,2,3,4-tetrahydro-4-oxo-6-(5-substituted 2-phenyl-1H-indol-3-yl)-2-thioxopyrimidine-5-carbonitrile as antimicrobial and antitubercular agent (Record no. 19314)

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005 - DATE AND TIME OF LATEST TRANSACTION
control field 20230509112552.0
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040 ## - CATALOGING SOURCE
Original cataloging agency AIKTC-KRRC
Transcribing agency AIKTC-KRRC
100 ## - MAIN ENTRY--PERSONAL NAME
9 (RLIN) 20696
Author Walmik, Prabhaker
245 ## - TITLE STATEMENT
Title Design of an efficient three component one-pot synthesis of -1,2,3,4-tetrahydro-4-oxo-6-(5-substituted 2-phenyl-1H-indol-3-yl)-2-thioxopyrimidine-5-carbonitrile as antimicrobial and antitubercular agent
250 ## - EDITION STATEMENT
Volume, Issue number Vol.61(10), Oct
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Place of publication, distribution, etc. New Delhi
Name of publisher, distributor, etc. CSIR
Year 2022
300 ## - PHYSICAL DESCRIPTION
Pagination 1134-1138p.
520 ## - SUMMARY, ETC.
Summary, etc. In the present study, a novel, rapid, improved and eco-friendly synthesis of indolyl-pyrazolo-pyrimidine derivatives 4a-c by using conventional method via one-pot multi-component reaction has been described. The structures of all these unknown compounds have been confirmed with the help of physical and spectroscopic techniques like IR, 1H and 13C NMR and mass spectrometry and these newly synthesized compounds have been evaluated for in vitro antimicrobial and antitubercular and antioxidant activities. The results reveal that compound 4a exhibits promising antimicrobial, antitubercular and antioxidant properties when compared to the standard drugs.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
9 (RLIN) 5009
Topical term or geographic name entry element GENERAL CHEMISTRY
773 0# - HOST ITEM ENTRY
International Standard Serial Number 0019-5103
Title Indian journal of chemistry (Section B)
Place, publisher, and date of publication New Delhi NISCAIR-CSIR 2005
856 ## - ELECTRONIC LOCATION AND ACCESS
URL http://op.niscpr.res.in/index.php/IJC/article/view/67200
Link text Click here
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme
Koha item type Articles Abstract Database
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          School of Pharmacy School of Pharmacy Archieval Section 2023-05-09 2023-0821 2023-05-09 2023-05-09 Articles Abstract Database
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