Clinical efficacy evaluation and long-term prognosis of glucagon-like peptide-1 combined with sodium glucose cotransporter-2 inhibitor in diabetes (Record no. 19407)
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| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | OSt |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20230523095821.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 230523b xxu||||| |||| 00| 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | AIKTC-KRRC |
| Transcribing agency | AIKTC-KRRC |
| 100 ## - MAIN ENTRY--PERSONAL NAME | |
| 9 (RLIN) | 20885 |
| Author | Yan, Pi |
| 245 ## - TITLE STATEMENT | |
| Title | Clinical efficacy evaluation and long-term prognosis of glucagon-like peptide-1 combined with sodium glucose cotransporter-2 inhibitor in diabetes |
| 250 ## - EDITION STATEMENT | |
| Volume, Issue number | Vol.84(4), Jul-Aug |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Mumbai |
| Name of publisher, distributor, etc. | Indian Journal of Pharmaceutical Science |
| Year | 2022 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Pagination | 812-820p. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | To investigate the clinical worth of glucagon-like peptide-1 receptor agonist (liraglutide) combined with sodium glucose cotransporter-2 inhibitor (dapagliflozin) in the treatment of overweight or obesity patients with type 2 diabetes mellitus and to explore whether the beneficial effect of the combination can persist during a 1 y follow-up. Eighty overweight or obesity type 2 diabetes mellitus patients admitted to a hospital from January 2019 to January 2020 were randomly divided into a control group and an observation group, with 40 cases in each group. The control group was treated with liraglutide and the experimental group was treated with basic dapagliflozin in the control group. All patients were continuously treated for 12 w. The measurement results of parameters before and after treatment, the changes in glucose metabolism parameters, blood lipid metabolism parameters and the occurrence of adverse reactions during treatment were recorded. After that, 74 treated patients were followed up for 1 y (6 refused) and measurements of various parameters were recorded. The differences in body mass index, waist circumference, hemoglobin A1c, fasting plasma glucose, triglyceride, total cholesterol, high-density lipoprotein cholesterol, low- density lipoprotein cholesterol, homeostatic model assessment-insulin resistance, homeostatic model assessment-beta and insulin sensitivity index before and after treatment in the experimental group were higher than those in the control group (p<0.05). Weight loss during treatment was sustained over 1 y in both groups, with more significant changes in the experimental group. The combination of glucagon-like peptide-1 agonist and sodium glucose cotransporter-2 inhibitor can improve diabetes in overweight or obesity patients with type 2 diabetes mellitus and effectively reduce blood glucose and body mass index, which is of great significance for reducing body weight and improving efficacy. Therefore, using glucagon- like peptide-1 agonists and sodium glucose cotransporter-2 inhibitors in overweight, diabetic patients is a promising option. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| 9 (RLIN) | 4639 |
| Topical term or geographic name entry element | PHARMACEUTICS |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| 9 (RLIN) | 20886 |
| Co-Author | Ting, Ting Du |
| 773 0# - HOST ITEM ENTRY | |
| International Standard Serial Number | 0250-474X |
| Place, publisher, and date of publication | New Delhi Indian Pharmaceutical Association |
| Title | Indian journal of pharmaceutical sciences |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| URL | https://www.ijpsonline.com/articles/clinical-efficacy-evaluation-and-longterm-prognosis-of-glucagonlike-peptide1-combined-with-sodium-glucose-cotransporters.pdf |
| Link text | Click here |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | |
| Koha item type | Articles Abstract Database |
| Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Permanent Location | Current Location | Shelving location | Date acquired | Barcode | Date last seen | Price effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| School of Pharmacy | School of Pharmacy | Archieval Section | 2023-05-23 | 2023-0838 | 2023-05-23 | 2023-05-23 | Articles Abstract Database |