Comparative study between intravenous clonidine and preservative free intravenous lignocaine in attenuation of pressor response to laryngoscopy and endotracheal intubation (Record no. 19465)
[ view plain ]
| 000 -LEADER | |
|---|---|
| fixed length control field | a |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | OSt |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20230526145052.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 230526b xxu||||| |||| 00| 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | AIKTC-KRRC |
| Transcribing agency | AIKTC-KRRC |
| 100 ## - MAIN ENTRY--PERSONAL NAME | |
| 9 (RLIN) | 20988 |
| Author | Vazhakalayil, Subha Teresa Jose |
| 245 ## - TITLE STATEMENT | |
| Title | Comparative study between intravenous clonidine and preservative free intravenous lignocaine in attenuation of pressor response to laryngoscopy and endotracheal intubation |
| 250 ## - EDITION STATEMENT | |
| Volume, Issue number | Vol.13(4), Dec |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | New Delhi |
| Name of publisher, distributor, etc. | SAGE |
| Year | 2022 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Pagination | 382-387p. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | ObjectivesTo compare the attenuation of pressor responses by intravenous clonidine and preservative-free lignocaine to laryngoscopy and endotracheal intubation. Materials and MethodsA randomized, prospective, comparative, double-blinded study was conducted in 80 adult patients who were randomized into two groups of 40 each, group clonidine (Group C) and group lignocaine (Group L). Group C patients were given 2 µg/kg clonidine in 20 ml of normal saline as a slow infusion over 10 min prior to intubation. Group L patients were given 1.5 mg/kg of preservative-free 2% lignocaine in 20 ml of normal saline as a single-dose infusion over 3 min prior to intubation. Baseline vital and hemodynamic parameters were monitored during the perioperative period at 1-, 5-, and 10-min post-intubation. ResultsThe attenuation of heart rate (HR) after intubation was much better with clonidine than lignocaine as there is statistically significant difference in the mean HR between the two groups at 1, 5, and 10 min after intubation with the HR significantly lesser in the Group C than the Group L at all times after intubation. Both clonidine and lignocaine were effective in attenuating systolic blood pressure response after intubation, but clonidine was more effective than lignocaine as systolic blood pressure (SBP), diastolic blood pressure (DBP), and mean arterial pressure (MAP) in the Group C remained much lower than the Group L and the difference between the two groups was statistically significant at all times after intubation. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| 9 (RLIN) | 4774 |
| Topical term or geographic name entry element | PHARMACOLOGY |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| 9 (RLIN) | 20989 |
| Co-Author | Haroon, Shahbaz |
| 773 0# - HOST ITEM ENTRY | |
| Place, publisher, and date of publication | New Delhi SAGE Publications |
| Title | Journal of pharmacology and pharmacotherapeutics |
| International Standard Serial Number | 0976-500X |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| URL | https://journals.sagepub.com/doi/epub/10.1177/0976500X221148539 |
| Link text | Click here |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | |
| Koha item type | Articles Abstract Database |
| Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Permanent Location | Current Location | Shelving location | Date acquired | Barcode | Date last seen | Price effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| School of Pharmacy | School of Pharmacy | Archieval Section | 2023-05-26 | 2023-0882 | 2023-05-26 | 2023-05-26 | Articles Abstract Database |