Assessing the impacts of L-carnitine and modafinil on fatigue in Iraqi multiple sclerosis patients (Record no. 20219)

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control field OSt
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20231201143040.0
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fixed length control field 231201b xxu||||| |||| 00| 0 eng d
040 ## - CATALOGING SOURCE
Original cataloging agency AIKTC-KRRC
Transcribing agency AIKTC-KRRC
100 ## - MAIN ENTRY--PERSONAL NAME
9 (RLIN) 22261
Author Al-Shammari, Ahmed Hamza
245 ## - TITLE STATEMENT
Title Assessing the impacts of L-carnitine and modafinil on fatigue in Iraqi multiple sclerosis patients
250 ## - EDITION STATEMENT
Volume, Issue number Vol.14(3), Jul-Sep
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Place of publication, distribution, etc. Mumbai
Name of publisher, distributor, etc. Wolter Kluwer
Year 2023
300 ## - PHYSICAL DESCRIPTION
Pagination 226-228p.
520 ## - SUMMARY, ETC.
Summary, etc. Fatigue is a prevalent symptom experienced by individuals diagnosed with multiple sclerosis (MS), which greatly affects their daily activities and causes frustration and depression, thus affecting their lives and society. This can be prevented through the use of medicines such as L-carnitine and modafinil. The study aimed to examine the effect of L-carnitine and modafinil on fatigue and which one is better for MS patients. This was a clinical trial. This clinical trial was conducted in cooperation between Al-Kut University College and an MS consultant at Al-Zahraa Teaching Hospital in addition to the private neurological clinic from October 1, 2022, to March 15, 2023. Forty participants were split into two groups; both of which were almost identical characteristics regarding age, disease duration, and degree of fatigue. Group I (n = 20): relapsing-remitting MS patients with fatigue received modafinil. Group II (n = 20): relapsing-remitting MS patients with fatigue received L-carnitine. Fatigue was evaluated according to the Modified Fatigue Impact Scale (MFIS). The statistical work was done in SPSS (IBM Corp., Chicago, IL, USA, version 24). P values were calculated by the t-test. Significant data have P = 0.05. After 2 months of treatment, the results show a significant decrease in MFIS in both groups with a higher reduction in patients who use L-carnitine. Both modafinil and L-carnitine show a significant influence on fatigue in MS patients, and these effects are more in L-carnitine.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
9 (RLIN) 4639
Topical term or geographic name entry element PHARMACEUTICS
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9 (RLIN) 22262
Co-Author Abbood, Zainab A.
773 0# - HOST ITEM ENTRY
International Standard Serial Number 2231-4040
Title Journal of advanced pharmaceutical technology and research
856 ## - ELECTRONIC LOCATION AND ACCESS
URL https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10483915/
Link text Click here
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme
Koha item type Articles Abstract Database
Holdings
Withdrawn status Lost status Source of classification or shelving scheme Damaged status Not for loan Permanent Location Current Location Shelving location Date acquired Barcode Date last seen Price effective from Koha item type
          School of Pharmacy School of Pharmacy Archieval Section 2023-12-01 2023-1637 2023-12-01 2023-12-01 Articles Abstract Database
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