Anticancer potential of salacia chinensis l. and woodfordia fruticosa (l.) kurz of the western ghats forests of india (Record no. 20901)
[ view plain ]
| 000 -LEADER | |
|---|---|
| fixed length control field | a |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | OSt |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20240420112625.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 240420b xxu||||| |||| 00| 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | AIKTC-KRRC |
| Transcribing agency | AIKTC-KRRC |
| 100 ## - MAIN ENTRY--PERSONAL NAME | |
| 9 (RLIN) | 23265 |
| Author | Kc, Ninada |
| 245 ## - TITLE STATEMENT | |
| Title | Anticancer potential of salacia chinensis l. and woodfordia fruticosa (l.) kurz of the western ghats forests of india |
| 250 ## - EDITION STATEMENT | |
| Volume, Issue number | Vol.15(12), Dec |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Bhopal |
| Name of publisher, distributor, etc. | Innovare Academic Sciences Pvt Ltd |
| Year | 2023 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Pagination | 13-16p. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Objective: Salacia chinensis and Woodfordia fruticosa are medicinal plants from the Western Ghats of India traditionally used in the treatment of diabetes, diarrhea and worm infections. The current study aims to evaluate the cytotoxic potential of methanolic extract of Salacia chinensis and Woodfordia fruticosa against breast and pancreatic cancers. Methods: Methanolic extract of dried leaves of Salacia chinensis and Woodfordia fruticosa were obtained by Soxhlet extraction. The cytotoxic potential of the dried extract was evaluated against human breast (MDA-MB-231) and pancreatic (PANC-1) cancers in vitro using MTT-based assay. Results: The study showed a dose-dependent cytotoxicity of Salacia chinensis and Woodfordia fruticosa leaf extracts against breast and pancreatic cancers with IC50 values of 124 μg/ml against MDA-MB-231 and 230.5 μg/ml against PANC–1 cells, respectively. Conclusion: Results indicate the presence of cytotoxic phytochemicals in Salacia chinensis and Woodfordia fruticosa. Further purification of the extract might be beneficial to isolate the anticancer phytochemical. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| 9 (RLIN) | 4639 |
| Topical term or geographic name entry element | PHARMACEUTICS |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| 9 (RLIN) | 23266 |
| Co-Author | N, Bhagya |
| 773 0# - HOST ITEM ENTRY | |
| International Standard Serial Number | 2656-0097 |
| Place, publisher, and date of publication | Bhopal Innovare Academic Sciences Pvt Ltd |
| Title | International journal of pharmacy and pharmaceutical science |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| URL | https://journals.innovareacademics.in/index.php/ijpps/article/view/49198 |
| Link text | Click here |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | |
| Koha item type | Articles Abstract Database |
| Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Permanent Location | Current Location | Shelving location | Date acquired | Barcode | Date last seen | Price effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| School of Pharmacy | School of Pharmacy | Archieval Section | 2024-04-20 | 2024-0459 | 2024-04-20 | 2024-04-20 | Articles Abstract Database |