| 000 -LEADER |
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| fixed length control field |
a |
| 003 - CONTROL NUMBER IDENTIFIER |
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| control field |
OSt |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
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| control field |
20211223131024.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
181204b xxu||||| |||| 00| 0 eng d |
| 040 ## - CATALOGING SOURCE |
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| Original cataloging agency |
AIKTC-KRRC |
| Transcribing agency |
AIKTC-KRRC |
| 100 ## - MAIN ENTRY--PERSONAL NAME |
|---|
| 9 (RLIN) |
6543 |
| Personal name |
Singh, M. P. |
| 245 ## - TITLE STATEMENT |
|---|
| Title |
Investigation on antidiabetic and antioxidant activity of extract of leaves of amaranthus polygamus in streptozotocin induced diabetic rats |
| 250 ## - EDITION STATEMENT |
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| Edition statement |
Vol. 55 (10) |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
|---|
| Place of publication, distribution, etc. |
Mumbai |
| Name of publisher, distributor, etc. |
Indian Drug Manufacture's Association - IDMA |
| Date of publication, distribution, etc. |
2018 |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Extent |
49-55 |
| 520 ## - SUMMARY, ETC. |
|---|
| Summary, etc. |
The aim of the present study was to assess the antihyperglycemic and antioxidant activites of the methanol extracts of Amaranthus polygamus (MEAP). Indian folklore suggests the plant as good liver tonic and is recommended as vegetable for diabetic and anemic patients. MEAP was evaluated for antidiabetic activity by using streptozotocin (STZ)- induced diabetic rats. The administration of MEAP and glibenclamide (GLB) to diabetic rats for 21 days showed marked fall in serum glucose (SG) levels compared to basal values i.e. at 1st day. MEAP (400 mg/kg) and GLB (0.5 mg/kg) showed significant reduction(P<0.0001) in SG level (37.2% and 52.9%, respectively). MEAP (400 mg/kg) and GLB showed significant improvement in oral glucose tolerance test (OGTT) and slight elevation in SG level, but after 60 min it showed marked downfall over the period of 120 min in comparison with 30 min. MEAP also possesses some antioxidant activity IC50 = 47.80 μg/ml in DPPH assay.
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| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| 9 (RLIN) |
4639 |
| Topical term or geographic name entry element |
PHARMACEUTICS |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
Polygamus |
| -- |
Streptozotocin |
| -- |
Glibenclamide |
| -- |
Serum glucose |
| -- |
Antidiabetic |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
|---|
| 9 (RLIN) |
6548 |
| Personal name |
Shukla, S. T. |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
|---|
| 9 (RLIN) |
6549 |
| Personal name |
Pateriya, A. |
| 773 0# - HOST ITEM ENTRY |
|---|
| Host Biblionumber |
3285 |
| Host Itemnumber |
24625 |
| Place, publisher, and date of publication |
Mumbai Indian Drug Manufactures Association |
| Other item identifier |
BJ0042 |
| Title |
Indian drugs |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
|---|
| Source of classification or shelving scheme |
|
| Koha item type |
Articles Abstract Database |
