| 000 -LEADER |
|---|
| fixed length control field |
a |
| 003 - CONTROL NUMBER IDENTIFIER |
|---|
| control field |
OSt |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
|---|
| control field |
20181208104539.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
|---|
| fixed length control field |
181208b xxu||||| |||| 00| 0 eng d |
| 040 ## - CATALOGING SOURCE |
|---|
| Original cataloging agency |
AIKTC-KRRC |
| Transcribing agency |
AIKTC-KRRC |
| 100 ## - MAIN ENTRY--PERSONAL NAME |
|---|
| 9 (RLIN) |
6899 |
| Author |
Gadade, D. D. |
| 245 ## - TITLE STATEMENT |
|---|
| Title |
Solubility enhancement of ofloxacin by mixed solvency approach |
| 250 ## - EDITION STATEMENT |
|---|
| Volume, Issue number |
Vol. 55 (06) June |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
|---|
| Place of publication, distribution, etc. |
Mumbai |
| Name of publisher, distributor, etc. |
Indian Drug Manufacture's Association - IDMA |
| Year |
2018 |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Pagination |
34-40 |
| 520 ## - SUMMARY, ETC. |
|---|
| Summary, etc. |
In current study we attempted mixed solvency approach for solubility enhancement of poorly water soluble drug, ofloxacin. Various hydrotropic agents including sodium benzoate, urea, sodium citrate, sodium acetate, niaciniamide, Lignocaine hydrochloride, PEG6000, PEG-400 were evaluated under study for enhancing solubility of drug. Further effect of various blends of these hydrotropic agents on solubility of ofloxacin was studied. Aqueous injection of ofloxacin was prepared and evaluated for its antimicrobial effectiveness and stability. It was found that mixed solvency approach is useful in solubility enhancement of ofloxacin without affecting its antimicrobial properties. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| 9 (RLIN) |
4639 |
| Topical term or geographic name entry element |
PHARMACEUTICS |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
|---|
| 9 (RLIN) |
6900 |
| Co-Author |
Lohade, T. S. |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
|---|
| 9 (RLIN) |
6901 |
| Co-Author |
Lahoti, S. R. |
| 773 0# - HOST ITEM ENTRY |
|---|
| Place, publisher, and date of publication |
Mumbai Indian Drug Manufactures Association |
| Title |
Indian drugs |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
|---|
| Source of classification or shelving scheme |
|
| Koha item type |
Articles Abstract Database |
