| 000 -LEADER |
|---|
| fixed length control field |
a |
| 003 - CONTROL NUMBER IDENTIFIER |
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| control field |
OSt |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
|---|
| control field |
20181208120214.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
181208b xxu||||| |||| 00| 0 eng d |
| 040 ## - CATALOGING SOURCE |
|---|
| Original cataloging agency |
AIKTC-KRRC |
| Transcribing agency |
AIKTC-KRRC |
| 100 ## - MAIN ENTRY--PERSONAL NAME |
|---|
| 9 (RLIN) |
6910 |
| Author |
Srivastava, A. K. |
| 245 ## - TITLE STATEMENT |
|---|
| Title |
Determination of bioactive contents and in vitro antioxidant activity of poly herbal formulations |
| 250 ## - EDITION STATEMENT |
|---|
| Volume, Issue number |
Vol. 55 (06) June |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
|---|
| Place of publication, distribution, etc. |
Mumbai |
| Name of publisher, distributor, etc. |
Indian Drug Manufacture's Association - IDMA |
| Year |
2018 |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Pagination |
56-62 |
| 520 ## - SUMMARY, ETC. |
|---|
| Summary, etc. |
Free radicals are reactive molecules involved in many physiological processes and have been associated with many diseases, such as ageing, cancer, arthritis and liver injury and cardiac complications. The total phenolics content were found to be 34.4±0.10 and 27.6±1.20 mg gallic acid equivalent (GAE)/g and total flavonoids contents, total tannin contents were 24.7±0.25 & 18.1±1.20 RE/g and 12.31±0.25 & 9.48±1.85 GAE/g, respectively of polyherbal formulations (HAF-I & HAF-II). Free radical scavenging activity was determined according to the elimination of DPPH radicals and total phenol content was determined by the Folin–Ciocalteu reaction. The relative antioxidant ability of the polyherbal formulations were investigated through two in vitro models, such as antioxidant capacity by radical scavenging activity using, α, α-diphenyl-β-picrylhydrazyl (DPPH) and nitric oxide (NO) methods. The extracts were used at concentration 20, 40, 60, 80 and 100 μg/mL concentrations and radical scavenging activity was determined in terms of inhibition percentage. The IC50 (concentration required for 50% inhibition) were calculated for each radicals. The present study was designed to evaluate the free radical scavenging activity of hydro-alcoholic extracts of polyherbal formulations (HAF-I & HAF-II) various in vitro models using Ascorbic acid and Rutin as a reference. The In vitro free radical DPPH activities were found to 74.17±0.18 & 75.30±0.18 and NO antioxidant activity were found to 75.3±1.10 & 76.17±1.24 at maximum concentration of 100 μg/mL. The In vitro anti-oxidant activity of these polyherbal formulations may be due to the presence of polyphenols. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| 9 (RLIN) |
4639 |
| Topical term or geographic name entry element |
PHARMACEUTICS |
| 653 ## - Keywords |
|---|
| Keywords |
Herbal |
| 653 ## - Keywords |
|---|
| Keywords |
Inhibition |
| 653 ## - Keywords |
|---|
| Keywords |
Polyphenols |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
|---|
| 9 (RLIN) |
6911 |
| Co-Author |
Kaushik, D. |
| 773 0# - HOST ITEM ENTRY |
|---|
| Place, publisher, and date of publication |
Mumbai Indian Drug Manufactures Association |
| Title |
Indian drugs |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
|---|
| Source of classification or shelving scheme |
|
| Koha item type |
Articles Abstract Database |
