000 -LEADER |
fixed length control field |
a |
003 - CONTROL NUMBER IDENTIFIER |
control field |
OSt |
005 - DATE AND TIME OF LATEST TRANSACTION |
control field |
20181210155429.0 |
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
fixed length control field |
181210b xxu||||| |||| 00| 0 eng d |
040 ## - CATALOGING SOURCE |
Original cataloging agency |
AIKTC-KRRC |
Transcribing agency |
AIKTC-KRRC |
100 ## - MAIN ENTRY--PERSONAL NAME |
9 (RLIN) |
6946 |
Author |
Sai Priya D. |
245 ## - TITLE STATEMENT |
Title |
Novel Schiff's bases of substituted 2-Amino benzothiazoles: Design, synthesis and antimicrobial activity |
250 ## - EDITION STATEMENT |
Volume, Issue number |
Vol. 55 (04) April |
260 ## - PUBLICATION, DISTRIBUTION, ETC. |
Place of publication, distribution, etc. |
Mumbai |
Name of publisher, distributor, etc. |
Indian Drug Manufacture's Association - IDMA |
Year |
2018 |
300 ## - PHYSICAL DESCRIPTION |
Pagination |
18-26 |
520 ## - SUMMARY, ETC. |
Summary, etc. |
Novel Schiff’s bases bearing substituted 2-amino benzothiazole were synthesized by single step process through simple condensation of 2-amino benzothiazole and substituted benzaldehydes and further characterized by FTIR, 1HNMR, and Mass spectrometry data. Antimicrobial activity of compounds was performed by agar diffusion method against a panel of bacterial strains such as S. aureus, B. subtilis (Gram-positive bacteria), E. coli, P. aeruginosa (Gram-negative bacteria) and fungal strains such as C. albicans and A. niger. Compound S13 and S17 had shown potent antifungal activity against C. albicans and A. niger respectively among the novel Schiff’s base compounds when compared to standard, and S13 compound had only shown moderate antibacterial activity against S. aureus amongst all. Molecular docking study was carried out against C. albicans DHFR (Dihydrofolate Reductase) domain to confirm their activity. |
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
9 (RLIN) |
4639 |
Topical term or geographic name entry element |
PHARMACEUTICS |
653 ## - Keywords |
Keywords |
2-amino benzothiazoles |
700 ## - ADDED ENTRY--PERSONAL NAME |
9 (RLIN) |
6947 |
Co-Author |
Kini, S. G. |
700 ## - ADDED ENTRY--PERSONAL NAME |
9 (RLIN) |
6948 |
Co-Author |
Bhatt, V. G. |
773 0# - HOST ITEM ENTRY |
Title |
Indian drugs |
Place, publisher, and date of publication |
Mumbai Indian Drug Manufactures Association |
942 ## - ADDED ENTRY ELEMENTS (KOHA) |
Source of classification or shelving scheme |
|
Koha item type |
Articles Abstract Database |