Novel Schiff's bases of substituted 2-Amino benzothiazoles: Design, synthesis and antimicrobial activity (Record no. 7862)

000 -LEADER
fixed length control field a
003 - CONTROL NUMBER IDENTIFIER
control field OSt
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20181210155429.0
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 181210b xxu||||| |||| 00| 0 eng d
040 ## - CATALOGING SOURCE
Original cataloging agency AIKTC-KRRC
Transcribing agency AIKTC-KRRC
100 ## - MAIN ENTRY--PERSONAL NAME
9 (RLIN) 6946
Author Sai Priya D.
245 ## - TITLE STATEMENT
Title Novel Schiff's bases of substituted 2-Amino benzothiazoles: Design, synthesis and antimicrobial activity
250 ## - EDITION STATEMENT
Volume, Issue number Vol. 55 (04) April
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Place of publication, distribution, etc. Mumbai
Name of publisher, distributor, etc. Indian Drug Manufacture's Association - IDMA
Year 2018
300 ## - PHYSICAL DESCRIPTION
Pagination 18-26
520 ## - SUMMARY, ETC.
Summary, etc. Novel Schiff’s bases bearing substituted 2-amino benzothiazole were synthesized by single step process through simple condensation of 2-amino benzothiazole and substituted benzaldehydes and further characterized by FTIR, 1HNMR, and Mass spectrometry data. Antimicrobial activity of compounds was performed by agar diffusion method against a panel of bacterial strains such as S. aureus, B. subtilis (Gram-positive bacteria), E. coli, P. aeruginosa (Gram-negative bacteria) and fungal strains such as C. albicans and A. niger. Compound S13 and S17 had shown potent antifungal activity against C. albicans and A. niger respectively among the novel Schiff’s base compounds when compared to standard, and S13 compound had only shown moderate antibacterial activity against S. aureus amongst all. Molecular docking study was carried out against C. albicans DHFR (Dihydrofolate Reductase) domain to confirm their activity.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
9 (RLIN) 4639
Topical term or geographic name entry element PHARMACEUTICS
653 ## - Keywords
Keywords 2-amino benzothiazoles
700 ## - ADDED ENTRY--PERSONAL NAME
9 (RLIN) 6947
Co-Author Kini, S. G.
700 ## - ADDED ENTRY--PERSONAL NAME
9 (RLIN) 6948
Co-Author Bhatt, V. G.
773 0# - HOST ITEM ENTRY
Title Indian drugs
Place, publisher, and date of publication Mumbai Indian Drug Manufactures Association
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme
Koha item type Articles Abstract Database
Holdings
Withdrawn status Lost status Source of classification or shelving scheme Damaged status Not for loan Permanent Location Current Location Shelving location Date acquired Barcode Date last seen Price effective from Koha item type
          School of Pharmacy School of Pharmacy Archieval Section 2019-03-28 2018042 2019-06-19 2019-03-28 Articles Abstract Database
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