| 000 -LEADER |
|---|
| fixed length control field |
a |
| 003 - CONTROL NUMBER IDENTIFIER |
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| control field |
OSt |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
|---|
| control field |
20190314093423.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
181211b xxu||||| |||| 00| 0 eng d |
| 040 ## - CATALOGING SOURCE |
|---|
| Original cataloging agency |
AIKTC-KRRC |
| Transcribing agency |
AIKTC-KRRC |
| 100 ## - MAIN ENTRY--PERSONAL NAME |
|---|
| 9 (RLIN) |
6958 |
| Author |
Shah, N. V. |
| 245 ## - TITLE STATEMENT |
|---|
| Title |
Development of sirolimus coated eluting stent using abluminal coating technology |
| 250 ## - EDITION STATEMENT |
|---|
| Volume, Issue number |
Vol. 55 (04) April |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
|---|
| Place of publication, distribution, etc. |
Mumbai |
| Name of publisher, distributor, etc. |
Indian Drug Manufacture's Association - IDMA |
| Year |
2018 |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Pagination |
56-62 |
| 520 ## - SUMMARY, ETC. |
|---|
| Summary, etc. |
The current study focuses on the development of abluminal coated stent using blend of sirolimus and poly L-lactide-co-caprolactone as the biodegradable polymer. The abluminal coating of stents presume to reduce the systemic side effects and provide targeted tissue release. To compare outcome of abluminal coated stents, conformal coated stent was also prepared using similar technology. Scanning electron microscopy was carried out to differentiate the abluminal and conformal coating patterns. Both patterns showed smooth and uniform coating which remains intact with stent surface even after crimping and post-expansion. Drug content data acquired by HPLC represented uniformity of drug coating on coated stents. In vitro drug elution revealed that both coating patterns yield similar percentage of drug release however, abluminal coated stent required less amount of drug and polymer due to selective application at vascular injury area. The findings indicate that the abluminal coated stent may be the future technology for efficient delivery of certain drugs. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| 9 (RLIN) |
4639 |
| Topical term or geographic name entry element |
PHARMACEUTICS |
| 653 ## - Keywords |
|---|
| Keywords |
Drug eluting stent |
| 653 ## - Keywords |
|---|
| Keywords |
Biodegradable polymer |
| 653 ## - Keywords |
|---|
| Keywords |
Abluminal coating |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
|---|
| 9 (RLIN) |
6959 |
| Co-Author |
Jariwala, A. B. |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
|---|
| 9 (RLIN) |
6960 |
| Co-Author |
Raval, A. J. |
| 773 0# - HOST ITEM ENTRY |
|---|
| Title |
Indian drugs |
| Place, publisher, and date of publication |
Mumbai Indian Drug Manufactures Association |
| 856 ## - ELECTRONIC LOCATION AND ACCESS |
|---|
| Link text |
Click here |
| URL |
https://www.indiandrugsonline.org/issuesarticle-details?id=Nzgz |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
|---|
| Source of classification or shelving scheme |
|
| Koha item type |
Articles Abstract Database |
