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a |
| 003 - CONTROL NUMBER IDENTIFIER |
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OSt |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
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20190314114553.0 |
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181227b xxu||||| |||| 00| 0 eng d |
| 040 ## - CATALOGING SOURCE |
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AIKTC-KRRC |
| Transcribing agency |
AIKTC-KRRC |
| 100 ## - MAIN ENTRY--PERSONAL NAME |
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| 9 (RLIN) |
7261 |
| Author |
Li, Shanshan |
| 245 ## - TITLE STATEMENT |
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| Title |
Evaluation of Antifatigue Effects of 20(S)-Ginsenoside Rg3 in Forced Swimming Mice |
| 250 ## - EDITION STATEMENT |
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| Volume, Issue number |
Vol. 80(03), September-October |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
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| Place of publication, distribution, etc. |
Mumbai |
| Year |
2018 |
| Name of publisher, distributor, etc. |
Indian Journal of Pharmaceutical Science |
| 300 ## - PHYSICAL DESCRIPTION |
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| Pagination |
510-515 |
| 520 ## - SUMMARY, ETC. |
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| Summary, etc. |
The main objective of this study was to investigate the antifatigue effects of 20(S)-ginsenoside Rg3 using forced swimming test in mice. Male Kunming mice were randomly divided into four groups; a control and three 20(S)-ginsenoside Rg3-treated groups. The control group was given distilled water whereas the treated groups were given different doses of 20(S)-ginsenoside Rg3 (10, 20 and 40 mg/kg). Treatments were administered by gavage once a day lasting for 28 days. After 28 days, forced swimming tests were performed and fatigue related biochemical parameters were examined. The results showed that 20(S)-ginsenoside Rg3 significantly (P<0.05) prolong exhaustive exercise time, significantly decrease (p<0.05) the blood lactic acid and serum urea nitrogen levels, significantly increase (p<0.05) the levels of glycogen, superoxide dismutase, glutathione peroxidase and catalase in liver and muscle, as well as significantly (p<0.05) reduce malondialdehyde levels in liver and muscle. These findings suggested that 20(S)-ginsenoside Rg3 has antifatigue effects, and its antifatigue mechanisms could be related to the fact that 20(S)-ginsenoside Rg3 can activate energy metabolism, eliminate the accumulation of metabolites, and protect exercise-induced oxidative stress. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| 9 (RLIN) |
4639 |
| Topical term or geographic name entry element |
PHARMACEUTICS |
| 653 ## - Keywords |
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| Keywords |
Biochemical parameters |
| 653 ## - Keywords |
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| Keywords |
Mouse |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| 9 (RLIN) |
7262 |
| Co-Author |
Chan, Z. |
| 773 0# - HOST ITEM ENTRY |
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| Title |
Indian journal of pharmaceutical sciences |
| Place, publisher, and date of publication |
New Delhi Indian Pharmaceutical Association |
| International Standard Serial Number |
0250-474X |
| 856 ## - ELECTRONIC LOCATION AND ACCESS |
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| Link text |
Click here |
| URL |
http://www.ijpsonline.com/articles/evaluation-of-antifatigue-effects-of-20s-ginsenosiderg3-in-forced-swimming-mice-3493.html |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
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| Source of classification or shelving scheme |
|
| Koha item type |
Articles Abstract Database |
