| 000 -LEADER |
|---|
| fixed length control field |
a |
| 003 - CONTROL NUMBER IDENTIFIER |
|---|
| control field |
OSt |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
|---|
| control field |
20190314140241.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
|---|
| fixed length control field |
190221b xxu||||| |||| 00| 0 eng d |
| 040 ## - CATALOGING SOURCE |
|---|
| Original cataloging agency |
AIKTC-KRRC |
| Transcribing agency |
AIKTC-KRRC |
| 100 ## - MAIN ENTRY--PERSONAL NAME |
|---|
| 9 (RLIN) |
7189 |
| Author |
Jain, N. |
| 245 ## - TITLE STATEMENT |
|---|
| Title |
Enhacement of solubility profile of plumbagin containing tablet at different |
| 250 ## - EDITION STATEMENT |
|---|
| Volume, Issue number |
Vol. 55(12), December |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
|---|
| Place of publication, distribution, etc. |
Mumbai |
| Name of publisher, distributor, etc. |
Indian Drug Manufacture's Association - IDMA |
| Year |
2018 |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Pagination |
78-82 |
| 520 ## - SUMMARY, ETC. |
|---|
| Summary, etc. |
The aim of present study is to improve solubility profile of a poorly soluble anti-cancer natural product, plumbagin at colonic site through incorporation of β-cyclodextrin by preparing complexes by a number of methods. Natural compound plumbagin have lower solubility profile in various GIT medias i.e. 0.1 N HCl, at stomach and intestinal pH. Natural compound plumbagin containing β-cyclodextrin complexes prepared with a number of methods increased the solubility profile in different dissolution media. The nature of plumbagin complexes was ascertained by FTIR spectrum. The tablet formulation of plumbagin β-cyclodextrin complex (kneading method) was prepared and coated with pH sensitive polymer Eudragit L100 for colon targeting. Plumbagin β-cyclodextrin complex can be used in place of pure plumbagin for the preparation of colon targeted drug delivery system. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| 9 (RLIN) |
4639 |
| Topical term or geographic name entry element |
PHARMACEUTICS |
| 653 ## - Keywords |
|---|
| Keywords |
Plumbagin |
| 653 ## - Keywords |
|---|
| Keywords |
Freeze drying method |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
|---|
| 9 (RLIN) |
7665 |
| Co-Author |
Kori, M. L. |
| 773 0# - HOST ITEM ENTRY |
|---|
| Place, publisher, and date of publication |
Mumbai Indian Drug Manufactures Association |
| Title |
Indian drugs |
| 856 ## - ELECTRONIC LOCATION AND ACCESS |
|---|
| Link text |
Click here |
| URL |
https://www.indiandrugsonline.org/issuesarticle-details?id=ODgw |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
|---|
| Source of classification or shelving scheme |
|
| Koha item type |
Articles Abstract Database |
