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a |
| 003 - CONTROL NUMBER IDENTIFIER |
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OSt |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
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20190315092513.0 |
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190307b xxu||||| |||| 00| 0 eng d |
| 040 ## - CATALOGING SOURCE |
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AIKTC-KRRC |
| Transcribing agency |
AIKTC-KRRC |
| 100 ## - MAIN ENTRY--PERSONAL NAME |
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| 9 (RLIN) |
7881 |
| Author |
Donkor, Martin Ntiamoah |
| 245 ## - TITLE STATEMENT |
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| Title |
Effect of ethanol stem bark extract of berlinia grandiflora hutch and dalz on marker liver enzymes in rats treated with CCI 4 |
| 250 ## - EDITION STATEMENT |
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| Volume, Issue number |
Vol. 10(10), July-August |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
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| Place of publication, distribution, etc. |
M. P. |
| Name of publisher, distributor, etc. |
Innovare Academic Sciences Pvt Ltd |
| Year |
2018 |
| 300 ## - PHYSICAL DESCRIPTION |
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| Pagination |
69-73 |
| 520 ## - SUMMARY, ETC. |
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| Summary, etc. |
Objective: The objective of this work was to validate the traditional claim of the use of the stem bark of Berlinia grandiflorain treating liver problems by investigating the effect of its ethanol stem bark extract on maker liver enzymes in vivo. Methods: Groups of Wistar albino rats (6 in each group) were daily treated with CCl4 (2 ml/kg b.w., diluted with olive oil 1:1 v/v, intravenously), followed by oral administration of ethanol stem bark extract of Berlinia grandiflora (ESBG) at doses 100, 300 and 900 mg/kg b.w. respectively, 3 hafter the administration of the CCl4. Serum biochemical parameters were measured 24 h at the end of the 7-day treatment period and compared to a group intoxicated with CCl4 Results: Treatment of rats with ESBG (at doses 100, 300 and 900 mg/kg b.w. orally) reduced the impact of CCl(2 ml/kg b.w., diluted with olive oil 1:1 v/v, intravenously) alone.4-induced hepatotoxicity on liver maker enzymes Alanine aminotransferase (ALT), Aspartate aminotransferase (AST), Alkaline phosphatase (ALP) and total bilirubin (TB), with the 900 mg/kg b.w. showing a significant reduction (p<0.05) compared to the group intoxicated with CCl4. The extract reversed the impact of the CCl4-induced hepatotoxicity by increasing the concentration of the serum Total protein (TP) and albumin (ALB), with the 900 mg/kg b.w. dose showing a significant increment (p<0.05) compared to the group intoxicated with the CCl4Conclusion: The investigation of the effect of Berlinia grandifloraon CCl. 4Keywords: Aminotransferase, Berlinia grandiflora, Biochemical, CCl induced liver damage revealed that.... |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| 9 (RLIN) |
4639 |
| Topical term or geographic name entry element |
PHARMACEUTICS |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| 9 (RLIN) |
7882 |
| Co-Author |
Ayikanle, Samuel Yawson |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| 9 (RLIN) |
7883 |
| Co-Author |
Donkor, Samuel Adoesom |
| 773 0# - HOST ITEM ENTRY |
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| Place, publisher, and date of publication |
Bhopal Innovare Academic Sciences Pvt Ltd |
| International Standard Serial Number |
0975 – 1491 |
| Title |
International journal of pharmacy and pharmaceutical science |
| 856 ## - ELECTRONIC LOCATION AND ACCESS |
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| URL |
https://innovareacademics.in/journals/index.php/ijpps/article/view/27376/15890 |
| Link text |
Click here |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
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| Source of classification or shelving scheme |
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| Koha item type |
Articles Abstract Database |
