| 000 -LEADER |
|---|
| fixed length control field |
a |
| 003 - CONTROL NUMBER IDENTIFIER |
|---|
| control field |
OSt |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
|---|
| control field |
20190315101559.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
190312b xxu||||| |||| 00| 0 eng d |
| 040 ## - CATALOGING SOURCE |
|---|
| Original cataloging agency |
AIKTC-KRRC |
| Transcribing agency |
AIKTC-KRRC |
| 100 ## - MAIN ENTRY--PERSONAL NAME |
|---|
| 9 (RLIN) |
8007 |
| Author |
Vudhgiri, S. |
| 245 ## - TITLE STATEMENT |
|---|
| Title |
Synthesis and cytotoxicity evaluation of unusual mixture acid acetate-protected monogalactosyldiacylgly |
| 250 ## - EDITION STATEMENT |
|---|
| Volume, Issue number |
Vol. 80(6), November-December |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
|---|
| Place of publication, distribution, etc. |
Mumbai |
| Year |
2018 |
| Name of publisher, distributor, etc. |
Indian Journal of Pharmaceutical Science |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Pagination |
1143-1150 |
| 520 ## - SUMMARY, ETC. |
|---|
| Summary, etc. |
In the present study, acetate-protected monogalactosyldiacylglycerol and its fatty acid and aromatic acid analogues were synthesized using trichloroacetimidate methodology. All compounds synthesized were evaluated for cytotoxicity against four cancer cell lines and one normal cell line. Among the compounds tested, mixed acid compound 7b exhibited good activity with IC50 value of 27.5 μM. In a similar manner, the combination of unsaturated oleic acid and cinnamic acid compound 7d also exhibited significant activity with IC50 value 34.9 μM. Based on these results, it could be concluded that the combination of oleic acid with cinnamic acid type acid and other saturated fatty acids enhance the cytotoxicity of glycoglycerolipids. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| 9 (RLIN) |
4639 |
| Topical term or geographic name entry element |
PHARMACEUTICS |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
|---|
| 9 (RLIN) |
8008 |
| Co-Author |
Koude, D. |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
|---|
| 9 (RLIN) |
8009 |
| Co-Author |
Misra, S. |
| 773 0# - HOST ITEM ENTRY |
|---|
| Place, publisher, and date of publication |
New Delhi Indian Pharmaceutical Association |
| Title |
Indian journal of pharmaceutical sciences |
| International Standard Serial Number |
0250-474X |
| 856 ## - ELECTRONIC LOCATION AND ACCESS |
|---|
| URL |
http://www.ijpsonline.com/articles/synthesis-and-cytotoxicity-evaluation-of-unusual-mixture-acid-acetateprotected-monogalactosyldiacylglycerols-3574.html |
| Link text |
Click here |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
|---|
| Source of classification or shelving scheme |
|
| Koha item type |
Articles Abstract Database |
