In vivo antiinflammatory activity of exacum bicolor roxb. leaves (Record no. 8507)

000 -LEADER
fixed length control field a
003 - CONTROL NUMBER IDENTIFIER
control field OSt
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20190315102129.0
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 190312b xxu||||| |||| 00| 0 eng d
040 ## - CATALOGING SOURCE
Original cataloging agency AIKTC-KRRC
Transcribing agency AIKTC-KRRC
100 ## - MAIN ENTRY--PERSONAL NAME
9 (RLIN) 8012
Author Ashwini, A. M.
245 ## - TITLE STATEMENT
Title In vivo antiinflammatory activity of exacum bicolor roxb. leaves
250 ## - EDITION STATEMENT
Volume, Issue number Vol. 80(6), November-December
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Place of publication, distribution, etc. Mumbai
Year 2018
Name of publisher, distributor, etc. Indian Journal of Pharmaceutical Science
300 ## - PHYSICAL DESCRIPTION
Pagination 1156-1159
520 ## - SUMMARY, ETC.
Summary, etc. Leaves of Exacum bicolor are traditionally used as a remedy for the treatment of inflammatory disorders in the form of a tonic by the tribal community of Western Ghats of Karnataka. The present study was designed to evaluate the antiinflammatory activity of the methanol extract of Exacum bicolor leaf using the carrageenan-induced mice paw oedema model. The methanol extract which was shown earlier to possess in vitro antiinflammatory activity was further screened for in vivo antiinflammatory activity at doses of 250 and 500 mg/kg. Diclofenac sodium 10 mg/kg was used as the reference standard. The plant extract showed significant dose-dependent reduction in paw edema when compared to the control at all the time intervals, which was also comparable to that produced by diclofenac. Histopathological analysis revealed clear and distinguished cellular damage for all the groups. The results of the current study showed that the methanol extract of the leaf of Exacum bicolor possessed significant antiinflammatory potential, which provided supporting evidence to the folklore use of the plant leaves as an antiinflammatory drug.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
9 (RLIN) 4639
Topical term or geographic name entry element PHARMACEUTICS
700 ## - ADDED ENTRY--PERSONAL NAME
9 (RLIN) 8013
Co-Author Gowda, S. V.
700 ## - ADDED ENTRY--PERSONAL NAME
9 (RLIN) 8014
Co-Author Majumdar, Mala
773 0# - HOST ITEM ENTRY
Title Indian journal of pharmaceutical sciences
International Standard Serial Number 0250-474X
Place, publisher, and date of publication New Delhi Indian Pharmaceutical Association
856 ## - ELECTRONIC LOCATION AND ACCESS
URL http://www.ijpsonline.com/articles/iin-vivoi-antiinflammatory-activity-of-iexacum-bicolori-roxb-leaves-3576.html
Link text Click here
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme
Koha item type Articles Abstract Database
Holdings
Withdrawn status Lost status Source of classification or shelving scheme Damaged status Not for loan Permanent Location Current Location Shelving location Date acquired Barcode Date last seen Price effective from Koha item type
          School of Pharmacy School of Pharmacy Archieval Section 2019-03-30 2018456 2019-06-19 2019-03-30 Articles Abstract Database
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