Gastro-portective potential of flowers of hibiscus Rosa-Sinensis (L.) in mucosal lesion or rats (Record no. 8965)

000 -LEADER
fixed length control field a
003 - CONTROL NUMBER IDENTIFIER
control field OSt
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20190511121413.0
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 190511b xxu||||| |||| 00| 0 eng d
040 ## - CATALOGING SOURCE
Original cataloging agency AIKTC-KRRC
Transcribing agency AIKTC-KRRC
100 ## - MAIN ENTRY--PERSONAL NAME
9 (RLIN) 8417
Author Agrawal, K. K.
245 ## - TITLE STATEMENT
Title Gastro-portective potential of flowers of hibiscus Rosa-Sinensis (L.) in mucosal lesion or rats
250 ## - EDITION STATEMENT
Volume, Issue number Vol. 56(03), March
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Place of publication, distribution, etc. Mumbai
Name of publisher, distributor, etc. Indian Drug Manufacturers Association
Year 2019
300 ## - PHYSICAL DESCRIPTION
Pagination 25-31p.
520 ## - SUMMARY, ETC.
Summary, etc. study was conducted to evaluate the gastro-protective activity of aqueous (HAE) and ethanolic (HEE) extracts of Hibiscus rosa-sinensis Linn. (Malvaceae) flowers in experimental animals. Aqueous and ethanolic extracts were investigated for pylorus ligation and indomethacin induced ulcer models in albino wistar rats. The pH, gastric volume, ulcer index, ulcer score and free and total acidity were determined by pylorus ligation induced ulcer model and ulcer score, ulcer index and percentage protection were determined by Indomethacin induced ulcer model. Phytochemical screening of aqueous and ethanolic extracts were conducted for and it showed that extracts have alkaloids, glycosides, tannins, flavonoids and mucilage. Both the extracts at dose of 200 and 400mg/kg showed significant (P<0.05) reduction in gastric volume (1.20±0.17, 0.83±0.20, 0.90±0.12, 0.96±0.17) and ulcer index (1.50±0.19, 1.33±0.11, 2.16±0.03, 0.75±0.17, 0.92±0.22, 0.31±0.04, 0.42±0.06, 0.19±0.04) as compared to the control group (1.47±0.15, 3.00±0.21, 1.64±0.13) in both of the models. It can be concluded that both the extracts possess gastro-protective activity that might be due the presence of flavanoids, tannins and/or mucilage.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
9 (RLIN) 5021
Topical term or geographic name entry element DRUG STORE MANAGEMENT
700 ## - ADDED ENTRY--PERSONAL NAME
9 (RLIN) 8419
Co-Author Verma, A.
700 ## - ADDED ENTRY--PERSONAL NAME
9 (RLIN) 8420
Co-Author Singh, K.
773 0# - HOST ITEM ENTRY
Title Indian drugs
Place, publisher, and date of publication Mumbai Indian Drug Manufactures Association
856 ## - ELECTRONIC LOCATION AND ACCESS
URL https://www.indiandrugsonline.org/issuesarticle-details?id=OTA3
Link text Click here
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme
Koha item type Articles Abstract Database
Holdings
Withdrawn status Lost status Source of classification or shelving scheme Damaged status Not for loan Permanent Location Current Location Shelving location Date acquired Barcode Date last seen Price effective from Koha item type
          School of Pharmacy School of Pharmacy Archieval Section 2019-05-11 2018475 2019-06-19 2019-05-11 Articles Abstract Database
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