Evaluation of Hepatoprotective Activity of Zanthoxylum armatumon Paracetamol-induced Liver Toxicity in Rats (Record no. 9010)

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control field OSt
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20190515113831.0
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040 ## - CATALOGING SOURCE
Original cataloging agency AIKTC-KRRC
Transcribing agency AIKTC-KRRC
100 ## - MAIN ENTRY--PERSONAL NAME
9 (RLIN) 8535
Author Talluri, M. R.
245 ## - TITLE STATEMENT
Title Evaluation of Hepatoprotective Activity of Zanthoxylum armatumon Paracetamol-induced Liver Toxicity in Rats
250 ## - EDITION STATEMENT
Volume, Issue number Vol. 81(1), Jan-Feb
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Place of publication, distribution, etc. Mumbai
Name of publisher, distributor, etc. Indian Journal of Pharmaceutical Science
Year 2019
300 ## - PHYSICAL DESCRIPTION
Pagination 138-145p.
520 ## - SUMMARY, ETC.
Summary, etc. The present study was carried out to identify phytochemical compounds and to study the hepatoprotective activity of Zanthoxylum armatum rhizome. Phytochemical analysis was carried out using standard procedures to quantify total alkaloid and phenolic contents. Hepatoprotective activity was determined using paracetamol-induced hepatotoxicity in rats. Zanthoxylum armatum extracts showed the presence of steroids, terpenoids, flavonoids, alkaloids, glycosides, phenols, oils, tannins and carbohydrates. The methanol extract has more phenolic and alkaloid contents than other extracts. The methanol extract at 500 mg/kg showed greater hepatoprotective activity with 66.87, 64.84, 67.95, 60.76 and 65.85 % protection on aspartate aminotransferase, alanine aminotransferase, alkaline phosphatase, total bilirubin and total protein enzyme levels of the liver, respectively. The results of the present study and previous reports indicated that a variety of phytochemical constituents in Zanthoxylum armatum and its' extracts contributed to the observed antioxidant, antibacterial and hepatoprotective activities
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
9 (RLIN) 4639
Topical term or geographic name entry element PHARMACEUTICS
700 ## - ADDED ENTRY--PERSONAL NAME
9 (RLIN) 8536
Co-Author Gummadi, Veda Priya
700 ## - ADDED ENTRY--PERSONAL NAME
9 (RLIN) 8537
Co-Author Battu, G. R.
773 0# - HOST ITEM ENTRY
Title Indian journal of pharmaceutical sciences
International Standard Serial Number 0250-474X
Place, publisher, and date of publication New Delhi Indian Pharmaceutical Association
856 ## - ELECTRONIC LOCATION AND ACCESS
URL http://www.ijpsonline.com/articles/evaluation-of-hepatoprotective-activity-of-izanthoxylum-armatumi-on-paracetamolinduced-liver-toxicity-in-rats.pdf
Link text Click here
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme
Koha item type Articles Abstract Database
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          School of Pharmacy School of Pharmacy Archieval Section 2019-05-15 2018512 2019-06-19 2019-05-15 Articles Abstract Database
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